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2012 Program Booklet - MCD Biology - University of Colorado Boulder

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Keynote Speaker:<br />

William Freytag, PhD<br />

Former Chairman and CEO, Myogen,<br />

<strong>Boulder</strong>, CO<br />

Title: Fifteen Years and $1.3 Billion Later<br />

Friday, October 12<br />

5:10 – 6:10 pm<br />

JSCBB Butcher Auditorium<br />

Abstract:<br />

It is the mission <strong>of</strong> pharmaceutical research companies to take the path from understanding a<br />

disease to bringing a safe and effective new treatment to patients. Scientists work to piece<br />

together the basic causes <strong>of</strong> disease at the level <strong>of</strong> genes, proteins and cells. Out <strong>of</strong> this<br />

understanding emerge “targets”, which potential new drugs might be able to<br />

affect. Researchers work to: (i) validate these targets, (ii) discover molecules (potential drug)<br />

that interact with the chosen target, (iii) test these new compounds in the lab and clinic for<br />

safety and efficacy, and (iv) gain regulatory approval and get the drug into the hands <strong>of</strong><br />

doctors and patients. This whole process typically takes 10-­‐15 years and an expenditure <strong>of</strong><br />

$1.3 billion.

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