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PhD Thesis Demeter Zoltan

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Greene & Appel, 2006). In some CDV outbreaks, including the mass mortalities among<br />

Baikal and Caspian seals and large felids in the Serengeti Park, terrestrial carnivores,<br />

including dogs and wolves, have been suspected as vectors for the infectious agent<br />

(Kennedy et al., 2000; Kreutzer et al., 2008; Beineke et al., 2009).<br />

The virus is shed primarily by oro-nasal secretion, however, any discharge and<br />

secretion can carry the virus. CDV infects susceptible animals primarily by inhalation of<br />

airborne viruses or via infective aerosol droplets (Beineke et al., 2009).<br />

CDV is susceptible to ultraviolet light, although protein or antioxidants help<br />

protect it from inactivation. Extremely susceptible to heat and drying, CDV is destroyed<br />

by temperatures greater than 50-60 °C for 30 minutes, but survival times are longer at<br />

colder temperatures. In warm climates, CDV does not persist in kennels after infected<br />

dogs have been removed. The virus remains viable between pH 4.5-9, and it is<br />

susceptible to ether, chloroform, dilute (

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