PhD Thesis Demeter Zoltan

5.1.3 CPV2 infection
Pathological changes observed during the dissection of animals succumbed following a
CPV2 infection were represented by severe dehydration, anemia, evident signs of
diarrhea, severe inflammation of the anterior segment of the small intestine (duodenum
and jejunum), enlargement of the gallbladder, lymphadenopathy (especially in the
mesenteric lymph nodes) and the presence of a hemorrhagic or yellowish-brown
mucous content in the intestinal lumen (Fig. 9).
Fig. 9: Macroscopic changes induced by CPV2. A: anemia and evident enteritis
affecting the jejunum; B: abdominal organs of a dog showing signs of hemorrhagic
enteritis, lymphadenopathy and dilatation of the gall bladder; C: lymphoid depletion as
seen in a Peyer’s patch; D: cut section of an enlarged mesenteric lymph node with
hemorrhagic infiltration
5.2 Histopathology
Routine histopathological examination has been performed in all cases when complete
carcasses were available for examination. All findings were in accordance with the
changes described in the literature.
48