Molecular Devices Image Express Brochure_rev_B_LR.pdf

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multiple Imaging technologies address Specific needs thRee Image aCQUISItIon platFoRmS get the pICtURe RIght Choose the platform to match the image resolution and speed required for your research and highthroughput imaging needs. Research-quality optics and premium hardware performance are standard, Corporate Corporate whether 8222 you require widefield 8222 optics with a CCD camera; simultaneous 4-color, confocal scanning for ephys optical sectioning; or a telecentric ephys scan lens for 8181 8181 imaging thick optical sections. Capturing low- to high-resolution is easy with the ImageXpress ® Micro and ImageXpress Ultra Systems Flex Flex 8303 8303 that generate research-quality images at high speed and can be operated with 1X to 100X objective FlIpR FlIpR lenses. 8303 These systems provide the 8303 best X, Y and Z positioning available using voice coil motor movement lifeSci lifeSci with 8142 100 nm resolution to precisely 8142 locate and ImageXpress micro widefield System the ImageXpress micro System base unit; available options include cooled CCD and high-speed laser auto focus. Inset: ImageXpress micro System with environmental control and fluidics (top) and transmitted light (bottom) options. analyst 8243 Imaging 8263 Integrated analyst 8243 Imaging 8263 precision motion identify sub-cellular features and ensure excellent X, Y and Z repeatability. Pinpoint positioning simplifies multi-site time-lapse and tiling for large multi-image experiments. Rapid positioning, in combination with the laser autofocus option and an easy setup wizard, furnishes users with an intuitive interface to further Corporate improve overall workflow. 8222 The large-format IsoCyte High-Speed ephys Laser ephys 8181 8181 Scanning Cytometer is complimentary to the ImageXpress Microscopy Platforms, analyst providing analyst 8243 8243 versatility to the Complete Imaging Solution. The IsoCyte System brings cellular-resolution imaging to Flex Flex traditional high-throughput screening 8303 and cytometry 8303 applications, providing high-content data earlier in FlIpR FlIpR the drug discovery process. Regardless 8303 of where 8303the biology takes you, the MDS Analytical Technologies lifeSci lifeSci Complete Imaging Solution grows 8142 with your 8142 needs. Quality optics Imaging 8263 Corporate 8222 Imaging 8263 transfluor ® assay captured by the ImageXpress micro System. three-color overlay of motor neurons in culture captured on the ImageXpress micro System. wIDeFIelD ImagIng The ImageXpress Micro System is a versatile instrument offering an inverted widefield microscope with CCD camera options. Industry-leading stage and focus control, coupled with a high-speed laser autofocus option, make the ImageXpress Micro System the fastest and most precise automated CCD imaging station available. Combined with mature software, the ImageXpress Micro Instrument outperforms automated microscopes built from off-the-shelf components. Hardware options for environmental control and fluidics enable live cell assays and long time-lapse experiments. The ability to overlay fluorescence images on phase contrast images is possible with the transmitted light option. With so many possibilities, the ImageXpress Micro System is able to automate any fluorescent, bright field or phase contrast microscopy application. validated h i g h e r t h r o u g h p u t
Corporate 8222 ephys 8181 analyst 8243 Flex 8303 FlIpR 8303 lifeSci 8142 Imaging 8263 ImageXpress Ultra Confocal System Integrated the ImageXpress Ultra System is a four-channel confocal imager available with the following lasers: 405, 488, 532, 561, and 635 nm. Imaging on the ImageXpress Ultra System: overlays of single cell image (above) at 60x/1.4na oil (actin in green, nuclei in blue, and mitochondria in red) and a long format scan of U2oS cells from a transfluor assay (left). ConFoCal ImagIng The ImageXpress Ultra System is the only true pointsource, laser scanning confocal imaging platform configured for 4-color simultaneous HCS. Sequential and simultaneous scanning are both possible. When applicable, simultaneous scanning significantly improves Corporate acquisition 8222 speed. A configurable pinhole provides an advantage over spinning disk confocals by allowing fine ephys tuning of z-section thickness and signal strength 8181 to achieve the ideal speed and image quality for your assay. analyst The ImageXpress Ultra System shares a small 8243 footprint, precision X, Y and Z control, and high-speed laser autofocus technology with the ImageXpress Micro Flex 8303 System. Unique to the ImageXpress Ultra System is the ability to acquire continuous long scans up to a 1:32 FlIpR aspect 8303 ratio to track long detailed cellular processes. The ImageXpress Ultra System is the best-in-class choice for high-speed, research-quality confocal imaging for HCS. lifeSci 8142 Imaging 8263 precision motion Quality optics IsoCyte laser Scanning Cytometer the IsoCyte high-Speed laser Scanning Cytometer; choose from 405, 440, 488, 532, and 640 nm excitation wavelengths. Imaging on the IsoCyte System: Cells stained and imaged in “whole well” format in a 96-well plate (left) can be identified, counted, and classified. whole organisms, such as worms (c. elegans) can also be imaged (right). hIgh-SpeeD, laRge-FoRmat ImagIng The IsoCyte Laser Scanning Cytometer is a fast, automation-friendly system that enables real-time imaging for cell- and bead-based assays, array scanning, colony assays, small organisms and tissue slices. The system’s telecentric lens captures emissions from a 400-µm thick optical slices. This eliminates the need for focusing, and is ideal for Corporate large 8222cell populations, 3-D cultures or small organisms. In addition, high sensitivity is available in up to four channels to support multiplexed ephys assays and maximum experiment efficiency. Scanning is 8181 “format-independent” and an entire plate or slide (6- to 1536-well microplates analyst or slides) is imaged in 2–10 minutes depending on the 8243 selected image resolution. Object-based “on-the-fly” image analysis provides immediate results. The versatile IsoCyte System bridges Flex the 8303 gap between HCS applications and high-throughput imaging assays, expanding the range of high-content discovery to formats FlIpR beyond 8303 cellular assays. Images or data can be further analyzed with MetaXpress and AcuityXpress Software or exported in FCS format for plotting in any flow cytometry software. lifeSci 8142 Imaging 8263 validated mDS analytical technologies > 2 / 3
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