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The structure and function of serpins

The structure and function of serpins

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SVan <strong>of</strong> mice that rpominaouriy develop IDDM - nondese<br />

dlabeiic (NOD) mice.<br />

MECHANISMS OF AÏTACK<br />

By SIX memhi <strong>of</strong> age. mvghb 70 per cent <strong>of</strong> female <strong>and</strong> 10 per<br />

cHn <strong>of</strong> male NOD mice show features vep~ similar to thoie <strong>of</strong><br />

human IDDM. IDDM ran a110 be induced byvanrferd reif.<br />

reactive immuns cells imo idvh or newborn NOD mice Sinre<br />

na 41 NOD mice succumb to diabetes. <strong>and</strong> the incidence <strong>of</strong><br />

IDDM vatis signifanUy R lab populations amund the WO&. it<br />

s a*

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