Influence of Whisky Congeners on Health - The Institute of Brewing ...

markers related to uric acid metabolism, glucose metabolism, alcohol
metabolism and hepatic, pancreatic and renal functions. Alcohol and
acetaldehyde concentrations in blood were determined using a headspace gas
chromatography (type HS-101 8700), and oxypurine concentration in urine was
determined by colorimetry using a Hitachi type 736-15 automated analyzer.
Among the 13 subjects, seven healthy males[mean age: 31.9±1.9 (S.E), serum
uric acid: 5.0±0.3 mg/dL] who fulfilled the criteria specified in the study protocol
throughout the study period were used as the final evaluable subjects.
Alcohol intake at each drinking test (0.8 mL/kg body weight) was set at a level
slightly higher than the moderate amount <strong>of</strong> alcohol described in the NIAAA
review (2) (ca. 30.4 mL or less /male), taking into consideration the possible
individual difference in extrapolating the results <strong>of</strong> the study to healthy people
and patients in general. Except for low purine beer, each beverage used in the
study was commercially available and was purchased from a market.