Methods for Protein Structure Prediction - Fox Chase Cancer Center
Methods for Protein Structure Prediction - Fox Chase Cancer Center
Methods for Protein Structure Prediction - Fox Chase Cancer Center
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<strong>Fox</strong> <strong>Chase</strong> <strong>Cancer</strong> <strong>Center</strong><br />
Molecular Modeling Facility<br />
• Since April 2003, funded by NCI <strong>Cancer</strong> <strong>Center</strong> Support Grant and Pew<br />
Charitable Trusts<br />
• One staff member (Mark Andrake, Ph.D.)<br />
• Services:<br />
– <strong>Protein</strong> database search, multiple sequence alignments,<br />
orthologues/paralogues, phylogenetic trees<br />
– Homology modeling based on PDB templates<br />
– Secondary structure, coiled-coil, transmembrane topology prediction<br />
– Conservation analysis with structural interpretation<br />
– Interpretation and design of mutations<br />
– Docking of small molecules, proteins, nucleic acids<br />
– Text and images <strong>for</strong> papers and grants<br />
– Installation and instruction in structure visualization<br />
– Custom software <strong>for</strong> specific projects<br />
http://dunbrack.fccc.edu
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