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New Opportunities for Tin Use (cont’d)<br />
anImal healthcaRe<br />
Tin and zinc work well together to heal wounds and kill bacteria.<br />
A new range of animal healthcare products is being launched in<br />
the US, including pet and agricultural treatments. The biggest<br />
new use may be in footbaths for treating hoof rot in dairy cattle.<br />
A US-based company, Visions Marketing, is launching a range of<br />
animal healthcare formulations for preventing and treating skin<br />
diseases in bovine, equine, canine and other animal sectors.<br />
These formulations, comprising aqueous preparations of tin(II)<br />
fluoride and zinc sulphate, are patented and being marketed in<br />
the US under the ‘Accelerator’ trade name.<br />
Future developments, including human healthcare products,<br />
are already under consideration.<br />
44<br />
Building on Success: Developing Resources for the Future<br />
toothpaSte<br />
Tin is a key ingredient in ‘the world’s best toothpaste’. After years<br />
of research Oral-B launched ProExpert toothpaste, choosing<br />
tin to provide unique added benefits. Most toothpastes use<br />
normal fluoride but stannous fluoride also kills bacteria and fills<br />
microscopic holes in teeth.<br />
One of the longest established pharmaceutical uses of tin<br />
compounds is that of tin(II) fluoride and, to a lesser extent, tin(II)<br />
pyrophosphate, in toothpastes, dentifrices, topical solutions<br />
and mouthwashes. The US Food & Drug Administration (FDA)<br />
has approved tin(II) compounds in toothpastes at levels up<br />
to 0.4%, and the American Dental Association has approved<br />
topical treatments containing up to 8% tin(II) fluoride.<br />
The generic sector of oral healthcare has been highlighted<br />
as a likely growth area for tin chemicals in the medium<br />
term. In the late year or so there has been significant new<br />
patent activity by the major players in this market – Procter &<br />
Gamble, Unilever Colgate, Palmolive and Gaba International<br />
– all involving tin(II) salts in dental formulations.