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New Opportunities for Tin Use (cont’d)<br />

anImal healthcaRe<br />

Tin and zinc work well together to heal wounds and kill bacteria.<br />

A new range of animal healthcare products is being launched in<br />

the US, including pet and agricultural treatments. The biggest<br />

new use may be in footbaths for treating hoof rot in dairy cattle.<br />

A US-based company, Visions Marketing, is launching a range of<br />

animal healthcare formulations for preventing and treating skin<br />

diseases in bovine, equine, canine and other animal sectors.<br />

These formulations, comprising aqueous preparations of tin(II)<br />

fluoride and zinc sulphate, are patented and being marketed in<br />

the US under the ‘Accelerator’ trade name.<br />

Future developments, including human healthcare products,<br />

are already under consideration.<br />

44<br />

Building on Success: Developing Resources for the Future<br />

toothpaSte<br />

Tin is a key ingredient in ‘the world’s best toothpaste’. After years<br />

of research Oral-B launched ProExpert toothpaste, choosing<br />

tin to provide unique added benefits. Most toothpastes use<br />

normal fluoride but stannous fluoride also kills bacteria and fills<br />

microscopic holes in teeth.<br />

One of the longest established pharmaceutical uses of tin<br />

compounds is that of tin(II) fluoride and, to a lesser extent, tin(II)<br />

pyrophosphate, in toothpastes, dentifrices, topical solutions<br />

and mouthwashes. The US Food & Drug Administration (FDA)<br />

has approved tin(II) compounds in toothpastes at levels up<br />

to 0.4%, and the American Dental Association has approved<br />

topical treatments containing up to 8% tin(II) fluoride.<br />

The generic sector of oral healthcare has been highlighted<br />

as a likely growth area for tin chemicals in the medium<br />

term. In the late year or so there has been significant new<br />

patent activity by the major players in this market – Procter &<br />

Gamble, Unilever Colgate, Palmolive and Gaba International<br />

– all involving tin(II) salts in dental formulations.

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