Peritonitis Management in Children on PD Peritonitis Management ...

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Gram-negative bacteria on culture Stop vancomyc<strong>in</strong> or teicoplan<strong>in</strong> Pseudomonas sp. E.coli, Proteus sp., or Klebsiella sp. E.coli, Proteus sp., or Klebsiella sp. resistant to 3 rd generation cephalospor<strong>in</strong>s Other s<strong>in</strong>gle gramnegative bacteria • Cont<strong>in</strong>ue cefepime or ceftazidime • Add second agent • Cont<strong>in</strong>ue cefepime, ceftazidime or cefazol<strong>in</strong> if susceptible • Discont<strong>in</strong>ue ceftazidime • Treat with cefepime, imipenem or fluoroqu<strong>in</strong>olone • Treat based on susceptibilities
Antibiotic Dos<strong>in</strong>g Recommendations for the Treatment of <strong>Peritonitis</strong> Cont<strong>in</strong>uous Therapy Intermittent Therapy Load<strong>in</strong>g Dose Ma<strong>in</strong>tenance Dose Am<strong>in</strong>oglycosides (IP) Gentamic<strong>in</strong> 8 mg/L 4 mg/L Netilmyc<strong>in</strong> Tobramyc<strong>in</strong> 8 mg/L 8 mg/L 4 mg/L 4 mg/L anuric: 0.6 mg/kg non-anuric: 0.75 mg/kg Amikac<strong>in</strong> 25 mg/L 12 mg/L Cephalospor<strong>in</strong>s (IP) Cefazol<strong>in</strong> 500 mg/L 125 mg/L 20 mg/kg Cefepime 500 mg/L 125 mg/L 15 mg/kg Cefotaxime Ceftazidime 500 mg/L 500 mg/L 250 mg/L 125 mg/L 30 mg/kg 20 mg/kg Glycopeptides (IP) Vancomyc<strong>in</strong> 1000 mg/L 25 mg/L 30 mg/kg; Repeat dos<strong>in</strong>g: Teicoplan<strong>in</strong> 400 mg/L 20 mg/L 15 mg/kg every 3-5 days 15 mg/kg every 5-7 days Penicill<strong>in</strong>s (IP) Ampicill<strong>in</strong> -- 125 mg/L -- Qu<strong>in</strong>olones (IP) Ciprofloxac<strong>in</strong> 50 mg/L 25 mg/L -- Consensus Guidel<strong>in</strong>es, Perit Dial Int, 2012
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Peritonitis <stron
Page 4:
Nelson-Atkins Muse
Page 9 and 10:
Months Between Peritonitis<
Page 11 and 12:
Hospitalization Causes in</
Page 13: Patient Mortality on Dialysis PD In
Page 16 and 17: www.peritonitis.org
Page 18 and 19: Peritonitis Episod
Page 21: Pediatric Peritonitis</stro
Page 24 and 25: Rating Guidel<stro
Page 26 and 27: n n n Train<strong
Page 30 and 31: Retrainin<
Page 32 and 33: Guideline 2 Cathet
Page 36 and 37: Gram Negative Peritonitis</
Page 38 and 39: Intravenous antibiotic prophylaxis
Page 40 and 41: Guideline 4 Chroni
Page 42 and 43: Exit-Site Infections per Patient Ye
Page 44 and 45: Guideline 6 Adjunc
Page 46: Touch Contaminatio
Page 49: Guideline 7 Ostomy
Page 53 and 54: Prophylaxis for PEG Insertion Anti-
Page 55 and 56: Ciprofloxacin Imip
Page 57 and 58: Guideline 10 Empir
Page 59 and 60: Empiric Therapy Pediatric Start <st
Page 61 and 62: In vitro Resistance Rates 80 60 40
Page 63: Gram-positive bacteria on culture S
Page 67 and 68: Culture-Negative Peritoniti
Page 69 and 70: Rationale for Discontin</st
Page 71 and 72: Guideline 15 Relap
Page 73 and 74: Relapsing
Page 75 and 76: Indications for Catheter Removal fo
Page 77 and 78: Exit-site / Tunnel Infection
Page 79 and 80: Guideline 18 Diagn
Page 81 and 82: Oral Antibiotics Used in</s
Page 84: 1. Children’s Ho
Page 89 and 90: Causative Organisms at Exit-Site %
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