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Toxoplasmosis during pregnancy - IMD Berlin

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Institut für Medizinische Diagnostik<br />

<strong>Berlin</strong> - Potsdam MVZ GbR<br />

Is it possible to treat the infection <strong>during</strong><br />

<strong>pregnancy</strong>?<br />

Depending on the stage of <strong>pregnancy</strong>,<br />

treatment with specific antibiotics is possible in<br />

cases of a new toxoplasma gondii infection<br />

that may prevent damage to the unborn<br />

child.<br />

issued by:<br />

<strong>Toxoplasmosis</strong> <strong>during</strong><br />

<strong>pregnancy</strong><br />

How can an infection be prevented when<br />

there are no protective antibodies?<br />

- Refrain from eating raw or insufficiently<br />

heated meat (mincemeat, ground pork,<br />

salami etc.)<br />

- Have cat litter boxes cleaned daily<br />

(not by the pregnant woman)<br />

- Observe basic hygiene rules after<br />

preparing meat and working in the<br />

garden (wash hands etc.)<br />

- Your doctor arranges control checks<br />

Surgery stamp<br />

General information<br />

For patients insured by the public health system:<br />

Some medical services cannot be assumed by the medical<br />

insurance companies or not in every case (e.g. at own request)<br />

and therefore must be paid by the patient.<br />

Please refer to the order form for the fees for individual medical<br />

services.<br />

Please be advised that additional diagnoses are necessary<br />

should there be evidence of IgM antibodies. The doctor in<br />

charge stipulates the extent of the procedures. Costs may<br />

deviate from the quote.<br />

For patients insured privately:<br />

The private medical insurance assumes the fees according to<br />

current medical fee schedule provided there has been no prior<br />

exclusion of benefits.<br />

Should you have any queries your doctor is able to advise you.<br />

Further information concerning toxoplasmosis in<br />

cats are to be found in the flyer ‘Toxoplasmose bei<br />

der Katze’ (‘<strong>Toxoplasmosis</strong> in Cats’) from the<br />

Institut für Veterinämedizinische Diagnostik<br />

(Institute for veterinary Diagnostics).<br />

Institut für Medizinische Diagnostik<br />

<strong>Berlin</strong> - Potsdam MVZ GbR<br />

Nicolaistraße 22, 12247 <strong>Berlin</strong> (Steglitz)<br />

Tel (030) 77 001 322, Fax (030) 77 001 332<br />

Info@imd-<strong>Berlin</strong>.de, www.imd-berlin.de<br />

Friedrich-Ebert-Straße 33, 14469 Potsdam<br />

Tel (0331) 28095 0, Fax (0331) 28095 99<br />

info@imd-potsdam.de, www.medlab-pdm.de<br />

Our homepage provides information on other centres that take blood samples.<br />

Patient information<br />

Date: October 2012. Subject to change without notice.<br />

Laboratory medicine • Microbiology • Human genetics<br />

Transfusion medicine • Hygiene


What is toxoplasmosis?<br />

<strong>Toxoplasmosis</strong> is a contagious disease caused<br />

by the parasite Toxoplasma gondii.<br />

Humans are infected by oral ingestion at<br />

various stages of the parasite’s life, especially<br />

by consuming raw or insufficiently cooked meat<br />

containing cysts (mincemeat, salami). Cat<br />

faeces (e.g. via cat litter, sand or garden work)<br />

may cause ingestion of toxoplasma oocysts.<br />

Infection channels<br />

Cats (definitive host)<br />

Cat faeces<br />

Infection via oocysts in the earth<br />

Infection through meat<br />

containing oocysts<br />

Intrauterine Infection<br />

Infection of humans and warmblooded<br />

mammals occurs globally. In Germany ca. 70%<br />

of the population are diseased in the 60-65 age<br />

group.<br />

How do I recognise a toxoplasma gondii<br />

infection?<br />

Infection normally takes place without<br />

symptoms. Therefore there is no feeling of illness.<br />

Flu-like symptoms such as swelling of the lymph<br />

node, headache and muscle pain and general<br />

exhaustion are rare.<br />

Should a woman become infected with<br />

toxoplasma gondii <strong>during</strong> <strong>pregnancy</strong> the<br />

parasite may be passed on to the unborn child.<br />

Depending on the stage of the <strong>pregnancy</strong>,<br />

harm to the child is possible (cramps, change<br />

to the eyes, stillbirth).<br />

How does the diagnosis take place?<br />

The body produces specific antibodies in cases<br />

of infection by toxoplasma gondii.<br />

Evidence of IgG antibodies (protecting<br />

antibodies) indicates infestation by toxoplasma<br />

gondii. This does not constitute a risk for the<br />

unborn child.<br />

Evidence of IgG and IgM antibodies against<br />

toxoplasma gondii may indicate a recent<br />

infection.<br />

IgM antibodies may however still be detected<br />

years after an infection which initially is no<br />

reason for concern. Additional tests are<br />

necessary to confirm a new infection (e.g.<br />

avidity determination). This diagnosis is paid<br />

by your health insurance.<br />

When should determination of antibodies take<br />

place?<br />

Determination of IgG antibodies should take<br />

place optimally 3-4 months before or after<br />

<strong>pregnancy</strong>.<br />

There is danger for the unborn child should<br />

protecting antibodies be determined.<br />

Should you not possess protective antibodies<br />

then antibody checks (in 8-12 week intervals)<br />

should ensue <strong>during</strong> the entire <strong>pregnancy</strong>.

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