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Lecture 7: Reproductive and Developmental Toxicology (Yager)

Lecture 7: Reproductive and Developmental Toxicology (Yager)

Lecture 7: Reproductive and Developmental Toxicology (Yager)

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Distribution of Xenobiotics<br />

Between the Fetal <strong>and</strong> Maternal Compartments<br />

Maternal compartment<br />

Parent compound<br />

(Lipid soluble)<br />

Placenta<br />

Fetal compartment<br />

Parent compound<br />

(Lipid soluble)<br />

Polar metabolites<br />

Parent compound<br />

(Lipid soluble)<br />

Parent compound<br />

(Lipid soluble)<br />

Non-polar metabolites<br />

Non-polar metabolites<br />

Polar metabolites<br />

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