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Lecture 7: Reproductive and Developmental Toxicology (Yager)

Lecture 7: Reproductive and Developmental Toxicology (Yager)

Lecture 7: Reproductive and Developmental Toxicology (Yager)

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Environmental Estrogens<br />

Adverse<br />

reproductive<br />

effects<br />

150<br />

Sperm count<br />

(x10 6 /ml)<br />

100<br />

50<br />

0<br />

1930 1950 1970 1990<br />

61 studies over 52 years suggest declining sperm counts. Circle size reflects<br />

relative number of subjects.<br />

Source: adapted by CTLT from British Medical Journal, 1992.<br />

57

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