15th Annual Scientific Meeting - Heart Failure Society of America
15th Annual Scientific Meeting - Heart Failure Society of America
15th Annual Scientific Meeting - Heart Failure Society of America
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Sept. 19<br />
Monday<br />
Posters<br />
Posters<br />
Cardiovascular Physiology<br />
Posters<br />
Cardiovascular Physiology<br />
Sept. 19<br />
Monday<br />
Posters<br />
MondAY<br />
016 Interferon Regulatory Factor-3 (IRF-3) as a Potential<br />
Therapeutic Target To Prevent Myocyte Apoptosis and<br />
Promote Angiogenesis in Post-Myocardial Infarction<br />
Remodeling<br />
Ge<strong>of</strong>frey de Couto 1 , William Stanford 1 , Scott Heximer 1 , Jeffrey<br />
Medin 1 , Peter Liu 1 ; 1 University <strong>of</strong> Toronto, Toronto, ON, Canada<br />
017 Impaired Dobutamine Augmentation <strong>of</strong> Early Diastolic<br />
Suction in Diastolic Dysfunction<br />
Takahiro Ohara 1 , Cassie L. Niebel 2 , Kelley C. Stewart 2 , John J.<br />
Charonko 2 , Pamela R. Burgess 1 , Min Pu 1 , Pavlos P. Vlachos 2 ,<br />
William C. Little 1 ; 1 Cardiology Section, Wake Forest University<br />
School <strong>of</strong> Medicine, Winston-Salem, NC; 2 Department <strong>of</strong><br />
Mechanical Engineering, Virginia Tech, Blacksburg, VA<br />
018 The GRK2 Inhibitor βARKct Enhances β2-Adrenergic<br />
Receptor-Dependent Cardiac Contractility In Vivo by<br />
Opposing Receptor Interaction with Phosphodiesterase<br />
Type 4D<br />
Anastasios Lymperopoulos 1,2 , Giuseppe Rengo 2,3 , Erhe Gao 2 ,<br />
Walter J. Koch 2 ; 1 Pharmaceutical Sciences/College <strong>of</strong> Pharmacy,<br />
Nova Southeastern University, Fort Lauderdale, FL; 2 Center<br />
for Translational Medicine, Thomas Jefferson University,<br />
Philadelphia, PA; 3 University Federico II, Naples, Italy<br />
019 Diminished Global Arginine Bioavailability as a<br />
Metabolic Defect in Chronic <strong>Heart</strong> <strong>Failure</strong> in the Setting<br />
<strong>of</strong> Preserved Renal Function<br />
Kevin Shrestha 1 , Zhili Shao 1 , Allen G. Borowski 1 , Richard W.<br />
Troughton 2 , Allan L. Klein 2 , W.H. Wilson Tang 1 ; 1 Cleveland<br />
Clinic, Cleveland, OH; 2 Christchurch School <strong>of</strong> Medicine and<br />
Health Sciences, Christchurch, New Zealand<br />
020 TWIST-1 and Its Target, the miR 199/214 Cluster, Are<br />
Down-Regulated in Dilated Cardiomyopathy Resulting<br />
in Increased Proteasome Activity in Human Myocardium<br />
Anna Baumgarten 1 , Claudia Bang 2 , Reinhard Pregla 3 , Anika<br />
Tschirner 1 , Volker Adams 4 , Rudolf Meyer 3 , Thomas Thum 2 ,<br />
Roland Hetzer 3 , Stefan D. Anker 1 , Jochen Springer 1 ; 1 Applied<br />
Cachexia Research, CCR, Charite Medical School, Berlin,<br />
Germany; 2 Institute for Molecular and Translational Therapeutic<br />
Strategies, Medical School Hannover, Hannover, Germany;<br />
3<br />
DHZB, Berlin, Germany; 4 <strong>Heart</strong> Center Leipzig, Leipzig,<br />
Germany<br />
021 Nebulette Mutations Augment Cardiomyocyte Calcium<br />
Signaling through Modification <strong>of</strong> the Thin Filament in<br />
Preclinical Inherited Dilated Cardiomyopathy<br />
Kathryn M. Rafferty 1 , Evangalia G. Kranias 2 , Jeanne James 1 ,<br />
Jeffrey A. Towbin 1 , Enkhsaikhan Purevjav 1 ; 1 The <strong>Heart</strong> Institute,<br />
Cincinnati Childrens Hospital Medical Center, Cincinnati, OH;<br />
2<br />
Department <strong>of</strong> Pharmacology Cell Biophysics, University <strong>of</strong><br />
Cincinnati, Cincinnati, OH<br />
58<br />
022 Association between VE-VCO2 Slope and Resting<br />
Hemodynamic Measurements in Ambulatory <strong>Heart</strong><br />
<strong>Failure</strong> (HF) Patients: An Analysis from the Duke<br />
Advanced HF Database<br />
C. Patel 1 , R.J. Mentz 1 , J. Suarez 1 , A.F. Hernandez 1 , G.M. Felker 1 ,<br />
C.M. O’Connor 1 , J.G. Rogers 1 ; 1 Duke University, Durham, NC<br />
023 Obese Patients with Equivalent NYHA Have Less<br />
Cardiac Impairment Than Non-Obese Counterparts<br />
Shanmugakumar Chinnappa 1 , Nigel Lewis 1 , David Goldspink 2 ,<br />
Diane Barker 1 , Lip-Bun Tan 1 ; 1 Leeds Teaching Hospitals NHS<br />
Trust, Leeds, United Kingdom; 2 University <strong>of</strong> Leeds, Leeds,<br />
United Kingdom<br />
024 Fat Measurement and Functional Characteristics in<br />
<strong>Heart</strong> <strong>Failure</strong> Patients<br />
A. Zavin 1 , K. Allsup 1 , D.R. Gagnon 6,7 , R. Arena 4 , S. Davis 1 , J.<br />
Joseph 1,2 , S. Lecker 2 , A. Lazzari 1,3 , P.C. Schulze 5 , D.E. Forman 1,2 ;<br />
1<br />
VA Boston Healthcare System, Boston; 2 Harvard Medical<br />
School, Boston, MA; 3 Boston University School <strong>of</strong> Medicine,<br />
Boston, MA; 4 University <strong>of</strong> New Mexico, Albuquerque,<br />
NM; 5 Columbia University Medical Center, New York, NY;<br />
6<br />
Boston University SPH, Boston, MA; 7 VA Cooperative Studies<br />
Program, Boston, MA<br />
025 Pacing from a Novel Quadripolar LV Lead Improves LV<br />
Synchrony in CRT Patients<br />
Gery F. Tomassoni 1 , Melody Muir 1 , Erin O’Brien 2 , Kyungmoo<br />
Ryu 2 , Aaron Hesselson 1 ; 1 Lexington Cardiology Consultants,<br />
Lexington, KY; 2 St. Jude Medical, Sylmar, CA<br />
026 Hematological Malignancies Are Associated with<br />
Significant Elevations in N-Terminal Pro Brain<br />
Natriuretic Peptide<br />
Jesal Popat 1 , Abel Rivero 1 , Maya Guglin 1 ; 1 Department <strong>of</strong><br />
Cardiovascular Medicine, University <strong>of</strong> South Florida, Tampa,<br />
FL<br />
027 In Vitro and In Vivo Actions <strong>of</strong> a Novel ANP Genetic<br />
Variant: Unique Actions on Human Endothelial Cells<br />
Valentina Cannone 1 , Brenda K. Huntley 1 , Guido Boerrigter 1 ,<br />
Alessandro Cataliotti 1 , Denise M. Heublein 1 , John C. Burnett,<br />
Jr. 1 ; 1 Cardiorenal Research Laboratory, Mayo Clinic, Rochester,<br />
MN<br />
028 Left Atrial Diastolic Dysfunction, an Underappreciated<br />
Cause <strong>of</strong> Pulmonary Venous Hypertension and<br />
Decompensated <strong>Heart</strong> <strong>Failure</strong><br />
Hemal H. Kadakia 1 , Soheni Channah 1 , James T. Heywood 1 ,<br />
Allen D. Johnson 1 , Douglas N. Gibson 1 , Michael R. Smith 1 ,<br />
Tariq Khan 1 ; 1 Cardiology, Scripps Clinic, San Diego, CA<br />
59<br />
MondAY