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Molecular and cellular changes in acute kidney injury

Molecular and cellular changes in acute kidney injury

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Summary<br />

• Pre-Exist<strong>in</strong>g Levels of OS <strong>and</strong> Inflammation Determ<strong>in</strong>e<br />

the Amount <strong>and</strong> Type of Response to AKI (due to<br />

Tox<strong>in</strong>s, DN).<br />

• S<strong>in</strong>ce control of OS/Inflammation is critical <strong>in</strong> AKI,<br />

Pre-Exist<strong>in</strong>g OS should be recognized <strong>and</strong> treated<br />

first.<br />

• OS/Inflammation can be Reduced (with drugs <strong>and</strong>/or<br />

Low-AGE Diet).<br />

• Best Option? A Comb<strong>in</strong>ation of Drugs <strong>and</strong> Control of<br />

AGE Intake.<br />

18

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