Anaerobic Infections

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Tetanus • Clostridium tetani is found in soil and the normal gut flora of some mammals • Organism produces a potent exotoxin that causes powerful, sustained muscle contraction resulting in very painful muscle spasms (“spastic paralysis”) • Even tiny stimuli trigger spasms • Common name of disease: “lock jaw”
Facial spasm and risus sardonicus in a Filipino patient who has tetanus
Page 1 and 2: Anaerobic Infections George C. Meji
Page 5: Illustrative Case (continued)…
Page 8 and 9: Definitions • Aerobe • Facultat
Page 10 and 11: Facultative Anaerobes • Bacteria
Page 12 and 13: Microaerophile • Bacteria that re
Page 14 and 15: Importance of Aerotolerance 1. Clin
Page 16 and 17: Clinically Significant Anaerobes
Page 18 and 19: Fusobacterium nucleatum
Page 20 and 21: Aerobic / Anaerobic Sites • Gener
Page 22 and 23: Concept of Microenvironments • An
Page 24 and 25: Normal Gut Flora • Bacteroides sp
Page 26 and 27: Normal Mouth Flora • Usually thes
Page 28 and 29: Normal Genitourinary Flora • This
Page 30 and 31: Major Predisposing Condition • Al
Page 32 and 33: Predisposing Conditions • Unresol
Page 36: Tetanospasmin • Potent exotoxin,
Page 40 and 41: Wound Classification Clinical Featu
Page 42: Botulism • Due to environmental b
Page 45: Flaccid Paralysis due to Mild Botul
Page 48 and 49: Gas Gangrene • Due to Clostridium
Page 50: Case One: Gas Gangrene • A 35 yea
Page 53 and 54: C. perfringens growing on blood aga
Page 55: Case Two: Gas Gangrene • A 62 yea
Page 59 and 60: Pseudomembranous Colitis • Due to
Page 61 and 62: Peritonitis • Due to a mixture of
Page 63 and 64: Oral Abscess / Peridontal Disease
Page 66 and 67: Vestibular Abscess
Page 68: Bite Wounds • Human bite wounds a
Page 71 and 72: Brain Abscess • Commonly caused b
Page 74 and 75: Lung Abscess
Page 76 and 77: Endometritis and Septic Abortion
Page 78 and 79: Glove Box Used to Grow Anaerobes
Page 80 and 81: Treatment of Anaerobic Infections

Anaerobic Infections

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