Anaerobic Infections

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Endometritis and Septic Abortion • Endometritis is essentially the same thing as gangrene of the uterus caused by C. perfringens • Can occur after spontaneous abortion as well as procedures • Treat with surgical debridement (D & C = dilation and curettage) and antibiotics
Diagnosis of <strong>Anaerobic</strong> <strong>Infections</strong> • Key is obtaining a good specimen collected into anaerobic medium • Gram stain sometimes helpful • Identification may require specialized procedures – Gas chromatography in micro lab – Toxin identification
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Anaerobic Infections George C. Meji
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Illustrative Case (continued)…
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Definitions • Aerobe • Facultat
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Facultative Anaerobes • Bacteria
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Microaerophile • Bacteria that re
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Importance of Aerotolerance 1. Clin
Page 16 and 17:
Clinically Significant Anaerobes
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Fusobacterium nucleatum
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Aerobic / Anaerobic Sites • Gener
Page 22 and 23:
Concept of Microenvironments • An
Page 24 and 25:
Normal Gut Flora • Bacteroides sp
Page 26 and 27: Normal Mouth Flora • Usually thes
Page 28 and 29: Normal Genitourinary Flora • This
Page 30 and 31: Major Predisposing Condition • Al
Page 32 and 33: Predisposing Conditions • Unresol
Page 34 and 35: Tetanus • Clostridium tetani is f
Page 36: Tetanospasmin • Potent exotoxin,
Page 40 and 41: Wound Classification Clinical Featu
Page 42: Botulism • Due to environmental b
Page 45: Flaccid Paralysis due to Mild Botul
Page 48 and 49: Gas Gangrene • Due to Clostridium
Page 50: Case One: Gas Gangrene • A 35 yea
Page 53 and 54: C. perfringens growing on blood aga
Page 55: Case Two: Gas Gangrene • A 62 yea
Page 59 and 60: Pseudomembranous Colitis • Due to
Page 61 and 62: Peritonitis • Due to a mixture of
Page 63 and 64: Oral Abscess / Peridontal Disease
Page 66 and 67: Vestibular Abscess
Page 68: Bite Wounds • Human bite wounds a
Page 71 and 72: Brain Abscess • Commonly caused b
Page 74 and 75: Lung Abscess
Page 78 and 79: Glove Box Used to Grow Anaerobes
Page 80 and 81: Treatment of Anaerobic Infections
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Anaerobic Infections

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