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RASBURICASE: Single fixed dose or package insert dose?

RASBURICASE: Single fixed dose or package insert dose?

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<strong>RASBURICASE</strong><br />

Experience at Children’s Hospital of<br />

Michigan, USA<br />

Example: 147 kg 17 year old patient<br />

(IBW: 72 kg)<br />

Calculated <strong>dose</strong> at 0.15 mg/kg: 22 mg<br />

(using IBW: 10.8 mg)<br />

Gave one 10.5 mg <strong>dose</strong>: 0.07 mg/kg<br />

(ABW)

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