RASBURICASE: Single fixed dose or package insert dose?

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ALLOPURINOL Allopurinol is a xanthine oxidase inhibitor that prevents the conversion of hypoxanthine and xanthine to uric acid Has no effect on existing uric acid levels
RASBURICASE Rasburicase (recombinant urate oxidase) An enzyme that facilitates the conversion of uric acid to allantoin that is renally excreted. Allantoin is 5 – 10 times more soluble in urine than uric acid
Page 1 and 2: RASBURICASE: Single fixed dose or p
Page 3: HYPERURICEMIA Hydration Alkalinizat
Page 7 and 8: RASBURICASE Advantage: Rapidly elim
Page 9 and 10: RASBURICASE 0.15 or 0.2 mg/kg IV ov
Page 11 and 12: RASBURICASE Fixed Dose Some medical
Page 13 and 14: RASBURICASE 6 mg fixed dose for adu
Page 15 and 16: RASBURICASE Case report of 4.5 mg d
Page 17 and 18: RASBURICASE Experience of Northwest
Page 19 and 20: RASBURICASE Experience of Northwest
Page 21 and 22: RASBURICASE Concerns cont’d Would
Page 23 and 24: RASBURICASE Experience at Children
Page 27 and 28: RASBURICASE Reasons: low volume of
Page 31 and 32: RASBURICASE Conclusions What method

RASBURICASE: Single fixed dose or package insert dose?

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