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RASBURICASE: Single fixed dose or package insert dose?

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<strong>RASBURICASE</strong><br />

Experience at Children’s Hospital of<br />

Michigan, USA<br />

Advantages to this method?<br />

Eliminate need f<strong>or</strong> a repeat <strong>dose</strong> within<br />

24 to 48 hours, if at all<br />

Since the serum uric acid is below<br />

n<strong>or</strong>mal limits, would there be a<br />

decreased risk of a sudden increase in<br />

uric acid with chemotherapy<br />

administration?

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