Development and Application of Novel ... - Jacobs University
Development and Application of Novel ... - Jacobs University
Development and Application of Novel ... - Jacobs University
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PART I: CAPDE<br />
account the physical-<br />
signal<br />
chemical properties <strong>and</strong><br />
transduction<br />
evolutionary<br />
protein etc<br />
conservation.<br />
[38]<br />
The database provides<br />
information about<br />
HotSprint<br />
Database [39]<br />
hotspots in protein<br />
interface using<br />
conservation rate <strong>and</strong><br />
Numb PTB<br />
domain [39]<br />
http://prism.c<br />
cbb.ku.edu.tr/<br />
hotsprint/<br />
solvent accessibility <strong>of</strong><br />
the residues.<br />
Haloalkane<br />
dehalogenase<br />
HotSpot wizard<br />
[41]<br />
The web server predicts<br />
residue mutability <strong>of</strong><br />
functionally important<br />
residues <strong>and</strong> visualizes<br />
it on protein sequence<br />
<strong>and</strong> structure.<br />
,<br />
Phosphotries<br />
terase, 1,3-<br />
1,4-b-D-<br />
Glucan 4-<br />
glucanohydro<br />
lase, β-<br />
http://loschm<br />
idt.chemi.mun<br />
i.cz/hotspotwi<br />
zard/<br />
Lactamase<br />
[41]<br />
The web server detects<br />
Selecton [42]<br />
selection forces on<br />
biologically significant<br />
sites in the target<br />
protein during<br />
TRIM5α<br />
protein [42]<br />
http://selecto<br />
n.tau.ac.il/ind<br />
ex.html<br />
evolutionary process.<br />
Protein<br />
superfamily<br />
3DM [37]<br />
The database performs<br />
structure based MSA for<br />
α/β<br />
hydrolase<br />
http://3dmcsi<br />
s.systemsbiol<br />
12
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