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Statement of Ronald B. Herberman, MD Chairman of Board ...

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1 News ?<br />

Carcinogenicity <strong>of</strong> radi<strong>of</strong>requency electromagnetic fields<br />

In May, 2011, 30 scientrsts from<br />

14 coumries met atthe Internattonal<br />

Agency for Research on Cancer<br />

(IARC) In Lyon, France, to assess the<br />

carcinogenicity <strong>of</strong> radi<strong>of</strong>requency<br />

electromagnettc fields (RF-EMF)<br />

These assessmentsw~ll bepubllshed as<br />

Volume 102 <strong>of</strong>the IARC Monographs'<br />

Human exposures to RF-EMF<br />

(frequency range 30 kHz300 GHz) can<br />

occur from use <strong>of</strong> personal devices (eg,<br />

mobile telephones, cordless phones,<br />

Bluetooth, and amateur radios).<br />

from occupational sources (eg, hlgh.<br />

frequency d~elearic and lnduct~on<br />

heaters, and high-powered pulsed<br />

radars), and from envimnmental<br />

sources such as mobile-phone base<br />

statlow, broadcast antennas, and<br />

med~cdl applications. For workers,<br />

most emosure to RF-EMF comes from<br />

near-fierd sources, whereas thegeneral<br />

populat~on receives the h~ghest<br />

exposure from transmitters dose to<br />

the bodv, such as handheld devices like<br />

.<br />

mobile telephones. Exposure to high.<br />

power sources at work might involve<br />

highercumulative RF energy deposited<br />

into the body than exposure to mobile<br />

phones, butthe local energydeposited<br />

in the brain is generally less. Typical<br />

exposures to the brain from ro<strong>of</strong>top<br />

or tower-mounted mobilephone base<br />

stationsandfmmNandradibstations<br />

are several orders <strong>of</strong> magnitude<br />

lower than those from global system<br />

for mobile communications (GSM)<br />

handsets. The average exposure<br />

from use af digital enhanced cordless<br />

telecommunications (DECT) phones<br />

is around five times lower than that<br />

measured for GSM phones, and<br />

third-generation (3G) phones em<br />

it, on average, about 100 times less<br />

RF energy than GSM phones, when<br />

signals are strong. Similarly, the<br />

average output power <strong>of</strong> Btuetooth<br />

wireless hands-free krts is estimatedto<br />

be around 100 times lowerthan that<br />

<strong>of</strong> mobilephones.<br />

EMF5 genkrated by RF sources<br />

couple with the body, resulting in<br />

Induced electric and magnetic fields<br />

andassociated currents lns~de tissues.<br />

The most ~mportant factors that<br />

determ~ne the Induced fields are<br />

the distance <strong>of</strong> the source from the<br />

body and the output power level.<br />

Additionally, the efficiency <strong>of</strong> coupling<br />

and resulting field distribution inside<br />

the body strongly depend on the<br />

frequency, polarisation, and direction<br />

<strong>of</strong> wave incidence on the body, and<br />

anatomical features <strong>of</strong> the exposed<br />

person, including height, hodymass<br />

index, posture, and dielectric<br />

properties <strong>of</strong> the tissues. Induced<br />

fields within the body are highly nonun~form,<br />

varytng over several orders <strong>of</strong><br />

masn~tude, with local hotseotr<br />

Holding a mobile phone to the ear<br />

to makea voice call can result in high<br />

specific RF energy absorption-rate<br />

(SAR) values in the brain, depending<br />

on the design and position <strong>of</strong> the<br />

phone and its antenna in relation to<br />

the head, how the phone is held, the<br />

anatomy <strong>of</strong>the head, andthe quality<br />

<strong>of</strong> the link between the base station<br />

and phone. When used by children,<br />

the average RF energy deposition<br />

is two times higher in the brain and<br />

up to ten times higher in the bone<br />

marrow <strong>of</strong> the skull, compared with<br />

mobile phone use by adults? Use<br />

<strong>of</strong> hands-free kits lowers exposure<br />

to the brain to below 10% <strong>of</strong> the<br />

exposure from use at the ear, but it<br />

might increase exposure to other<br />

parts<strong>of</strong>the body?<br />

Epidemiological evidence for an<br />

association between RF-EMF and<br />

cancer comes from cohort, cash<br />

control, and time-trend studies. The<br />

populations in these studies were<br />

exposed to RF-EMF in occupational<br />

settings. from sources in the general<br />

environment, and fromuse<strong>of</strong>wireless<br />

(mobile and cordless) telephones.<br />

which is the most extensively studied<br />

exposure source. One cohort study'<br />

and five case-control studiesrg were<br />

judged by the Working Group to<br />

<strong>of</strong>fer potentially useful information<br />

@<br />

regarding associations between use <strong>of</strong><br />

wireless phones andglioma.<br />

The cohort study' inciuded2V cases<br />

<strong>of</strong> glioma among 420095 subscribers<br />

t~twoDanishmobilephonecompanies<br />

between 1982 and 1995. Glioma<br />

incidencewas nearthenationalaverage<br />

for the subscribers. In this study,<br />

reliance on subscription to a mobile P&II,~~O~I~~~<br />

phone ~rovider, as a surrogate for J""*ZI.~OI~<br />

mobile phone use, could have resulted ~~$'~~~~~~<br />

in considerable mivlassification in fama,eanthclrRC<br />

ewsure asses5ment Three early M ~ ~ ~ ~ ~ ~ ~ , . .<br />

case-control studies*' encompassed hwiimo~os.phria.~~vh~iar~~r~<br />

a period when mobile phone use was Upcominpmtt~tingr<br />

low, userstypically had low cumulative oal~-~a.mn<br />

erposurer, tlme since first use <strong>of</strong> a ~ ~ ~ ; ~ ; ~ t ~ ~ - ~ ~ ~<br />

moblle phone was short, and effect<br />

estimates were generally imprecise; P.bl.142iu<br />

the Working Group considered these ~o~wm~uiiua~[wqo,auc.ard<br />

studies less informative. Tme.trend ~~~~~mllvi~~~~liiundmal~riri<br />

analyses did not show an increased JU"S-u.zml<br />

rate<strong>of</strong> brain tumoursafterthe increase ~ ~ / ~ ~ ~<br />

in mobiie phone use. However, these MonaJnph<br />

roup<br />

studies have rubstantial limitations ~ t ~ b ~ ~<br />

because most<strong>of</strong>theanalysesexamined I Sam~-CM~lUSA):<br />

trends until the early 2000s only. Such ~ ~ ~ , ~ ~ ~ ~ o ~ ' ~ u<br />

analyses are uninformative If excess Pva~uraonri,r~.rrth..ve<br />

risk only manifests more than a decade 18elsiuml:l Siemia~Xi.<br />

after phone use beg~ns, or if phone ~ ~ ~ ~ " s ~ " , ~ ~ ~ , , m<br />

use only affects a small proportion <strong>of</strong> (finland) R ~ E S . 1 ~ iaore<br />

cases-eq.the mostheavllyemosed, . . or (Fiance) M Btettnw<br />

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