Genetic approaches to development - Society for Developmental ...
Genetic approaches to development - Society for Developmental ...
Genetic approaches to development - Society for Developmental ...
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Mis/overexpression screens, the good and the bad<br />
wrong gene --- right pathway<br />
Faf-lacZ; Gal4-driver<br />
X<br />
EP-UAS-insertion lines<br />
Expression<br />
in germ cells<br />
nos<br />
nos5’UTR<br />
Gal4-VP16<br />
nos3’UTR<br />
UAS<br />
Endogenous gene<br />
“mes”<br />
Gal4<br />
UAS<br />
Endogenous gene<br />
Expression<br />
in soma<br />
st 14 dorsal<br />
wild type<br />
a-Vasa<br />
over- or mis- expression
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