Genetic approaches to development - Society for Developmental ...
Genetic approaches to development - Society for Developmental ...
Genetic approaches to development - Society for Developmental ...
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Different Types of Mutageneses<br />
Mutagenic<br />
Advantages<br />
Disadvantages<br />
Effect<br />
EMS<br />
(and other<br />
chemicals)<br />
Base pair<br />
changes (point<br />
mutations)<br />
Random<br />
Saturation<br />
Different types of mutations<br />
Slow gene identification<br />
Large-scale<br />
P-elements<br />
(and other<br />
transposons)<br />
DNA Insertions<br />
(mostly<br />
hypomorphic)<br />
Fast gene identification<br />
Flexible scale<br />
No saturation<br />
Non-random (hotspots)<br />
Deficiency kit<br />
Chromosome<br />
Small-scale<br />
Slow gene identification<br />
(and other<br />
aberrations)<br />
rearrangements<br />
(gene deletions)<br />
Fast screening<br />
Defined set<br />
No real saturation<br />
Ionizing<br />
radiations (Xrays,<br />
g-rays)<br />
Chromosome<br />
rearrangements<br />
(gene deletions)<br />
Random<br />
Gene deletions<br />
Slow gene identification<br />
No real saturation<br />
Inefficient