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Practitioner's Guide to Using Alpha-Stim Practitioner's Guide to ...

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Efficacy of Antidepressants<br />

Beyond the Placebo Response<br />

70<br />

Percent Improvement<br />

Over Placebo<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Prozac Paxil Zoloft Effexor Serzone <strong>Alpha</strong>-<strong>Stim</strong> ® CES<br />

5 Studies 12 Studies 3 Studies 6 Studies 8 Studies 8 Studies<br />

Kirsch I, Moore TJ, Scorboria A, and Nicholls SS. The Emperor’s New Drugs: an Analysis of Antidepressant Medication Data<br />

submitted <strong>to</strong> the FDA. Prevention and Treatment. 2002;5:1-11.<br />

Gilula ME, and Kirsch DL. Cranial Electrotherapy <strong>Stim</strong>ulation Review: A Safer Alternative <strong>to</strong> Psychopharmaceuticals in the<br />

Treatment of Depression. Journal of Neurotherapy. 2005;9(2):7-26.<br />

In addition <strong>to</strong> the prospective research,<br />

we have survey data from both doc<strong>to</strong>rs<br />

and patients. Forty-seven doc<strong>to</strong>rs<br />

reported their results on 500 patients<br />

in 22 diagnostic categories resulting in<br />

a 50-page analysis of that data published<br />

in the book The Science Behind<br />

Cranial Electrotherapy <strong>Stim</strong>ulation by<br />

Dr. Daniel L. Kirsch (2nd Ed. Medical<br />

Scope Publishing, Alberta 2002).<br />

That data correlates well with a peerreviewed<br />

outcome study of 2,500<br />

patients’ self reports published in the<br />

American Journal of Pain Management:<br />

11(2):62-66, 2001. For most diagnostic<br />

categories, both doc<strong>to</strong>rs and patients<br />

reported that 9 out of 10 patients<br />

had significant results based on the<br />

drug standard of a minimum of 25%<br />

improvement. However, most<br />

<strong>Alpha</strong>-<strong>Stim</strong> ® patients had at least 60%<br />

improvement in their symp<strong>to</strong>ms.<br />

Furthermore, clinical research tells us<br />

the technology is effective if it achieves<br />

a probability fac<strong>to</strong>r of at least P

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