HBM2010 - Organization for Human Brain Mapping

SCIENTIFIC PROGRAM
9:00 – 10:15
H1 & 2 (Level -1)
MORNING WORKSHOP
Retinotopic Mapping: Techniques, Current Concepts
and Research Trends
Chairs: Mark M. Schira, Prince of Wales Medical Research
Institute, Sydney, Australia and
Serge O. Dumoulin, Utrecht University, Utrecht,
The Netherlands
A key property of visual cortex is the existence of multiple
retinotopic maps. These maps are not simply an anatomical
property, but a key principle in the functional organization
of information processing. Reconstructing these maps in vivo,
Retinotopic mapping provides insight into cortical
organization, but also are a prerequisite for many
investigations of the visual system. Retinotopic maps further
serve as a model to elucidate more general principles of brain
function, such as plasticity and interspecies comparisons.
In this symposium we will introduce recent developments of
retinotopic mapping techniques such as i) high resolution,
ii) 7T and iii) model-based pRF techniques. We will discuss
current concepts and interspecies differences of retinotopic
cortex in humans and non-human primates including the
foveal confluence. Finally, we will highlight some recent
insights on clinical manifestations and cortical plasticity
based on current retinotopic concepts.
Learning Objectives
Having completed this workshop, participants will be
able to:
1. Understand techniques and methods used in
contemporary retinotopic mapping;
2. Learn the implications of the visual field maps
organization on general brain functions;
3. Discuss the comparisons between human and
non-human visual cortex; and
4. Understand some of the clinical implications of
retinotopic mapping
The Foveal Confluence, Organization, Algebraic Modeling
Functions, Simple Mapping Techniques
Mark M. Schira, Prince of Wales Medical Research Institute,
Sydney, Australia
Visual Cortex Reorganization After Injury: Lessons from
Primate fMRI
Stelios M. Smirnakis, Baylor College of Medicine,
Houston, TX, USA
Retinopic Mapping at 7 Tesla Magnetic Field Strength
Michael B. Hoffmann, University Magdeburg, Magdeburg,
Germany
Measuring Population Receptive Field Properties using fMRI:
Methods and Applications
Serge O. Dumoulin, Utrecht University, Utrecht,
The Netherlands
9:00 – 10:15
J & H3 (Level -1)
MORNING WORKSHOP
Human Intra-Cranial Electrophysiology (ICE) in
Mind/Brain Mapping – Linking Levels of Analysis from
Cells to Psychology
Chair: Ned T. Sahin, University of California-San Diego,
La Jolla, CA, USA
Description
This session will overview advantages of Intra-cranial
Electrophysiology (ICE) and highlight results in four cognitive
domains that were uniquely achievable with ICE. The study of
human cognition is severely limited by current methods.
Neuroimaging has transformed our gamut of addressable
questions yet still imposes limitations of temporal, spatial,
and physiological resolution. These translate into a limitation
on ‘algorithmic resolution’ or the types of computation that
we can observe in the brain. While direct recordings from
brain tissue are generally not possible in humans, and
aspects of cognition (e.g. language) have no useful animal
model, patients with electrodes implanted in their brains for
surgery (and who have normal cognitive abilities) provide a
unique opportunity to Link the Levels of inquiry. ICE allows
measurements from single unit activity (SUA) up to local-field
and brain-surface potentials (ICE ERPs). In conjunction with
non-invasive methods, it also allows us to ask what level(s)
actually best reveal mechanisms of cognition – since more
resolution is not always better. Finally, fine-scale ICE results
can inform non-invasive methods. For instance, if disparate
mental functions are traced to the same neural circuit, but
are compartmentalized in time rather than space, paradigms
for fMRI can and must be designed to manipulate those
functions temporally.
28 | HBM 2010 Program