infertility treatments, genes and chromosomes

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Analysis of mutations in the DNA sequence (causing gsingle g gene disorders)
PGD of single gene disorders Alternative to prenatal diagnosis ‐ avoids pregnancy termination >200 different single gene disorders diagnosed using PGD PGD for any disease provided the causative mutation is known First disease diagnosed – cystic fibrosis, 1992
Page 1 and 2: In vitro fertilisation and genetic
Page 3 and 4: Indications for IVF/ICSI Unexplaine
Page 5 and 6: Egg collection procedure
Page 7 and 8: Fertilization Mixing of sperm and e
Page 9 and 10: Embryo development 2‐cell embryo
Page 11 and 12: Genetic analysis of embryos
Page 13 and 14: Aneuploidy and IVF failure Chromoso
Page 15 and 16: Preimplantation genetic screening (
Page 17 and 18: Increase in implantation/pregnancy
Page 19 and 20: Problems with negative PGS studies
Page 21 and 22: Microarray comparative genomic hybr
Page 23 and 24: 46,XX‐10 +16 Microarray‐CGH (ar
Page 25: Blastocyst CGH‐ clinical results
Page 29 and 30: PGD of single gene disorders Diseas
Page 31 and 32: Cleavage stage biopsy •Used by ma
Page 33 and 34: Generalized Diagnostic Methodology

infertility treatments, genes and chromosomes

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