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haematology users' handbook - University College London Hospitals

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Haemostasis (page 6 of 6)<br />

Test Specimen type Key Factors<br />

affecting<br />

tests<br />

Notes<br />

Referenc<br />

e Range<br />

Out of<br />

hours<br />

service<br />

Time Limit<br />

for<br />

requesting<br />

additional<br />

tests from<br />

time of<br />

venesection<br />

Turnaround<br />

time from<br />

receipt of<br />

sample (in<br />

working<br />

days for<br />

non urgent<br />

requests)<br />

Thrombophilia screen<br />

Antithrombin,<br />

Protein C,<br />

Protein S,<br />

Lupus Anticoagulant,<br />

Cardiolipin Antibodies,<br />

Factor V Leiden,<br />

Prothrombin Gene<br />

Mutation, MTHFR<br />

mutation.<br />

Also Factor VII and X<br />

assays when patients<br />

are on warfarin.<br />

4 x 4.5ml<br />

Sodium<br />

Citrated<br />

samples<br />

+<br />

1 x 5ml SST<br />

sample<br />

+<br />

1 x 4.5ml<br />

EDTA<br />

Delayed<br />

receipt of<br />

sample.<br />

Plasma must<br />

be processed<br />

within 5<br />

hours of<br />

venesection.<br />

Warfarin and<br />

Heparin<br />

Acute illness<br />

may affect<br />

results of<br />

some tests<br />

These tests require authorisation<br />

unless the patient is a Haematology,<br />

NHNN or HASU patient: for all other<br />

patients, please contact the<br />

Haemostasis or Haematology SpR<br />

(bleep 7044 or 7000) for authorisation<br />

before taking samples.<br />

These tests can be requested<br />

individually.<br />

Samples for Factor V Leiden, MTHFR<br />

and Prothrombin Gene Mutation are<br />

sent from Haemostasis, UCLH to TDL<br />

Genetics<br />

Contact<br />

the<br />

laboratory<br />

Antithrombin,<br />

Protein C<br />

and Protein S<br />

only, by<br />

agreement<br />

with the<br />

Haematology<br />

Consultant<br />

on call and<br />

subject to<br />

staff<br />

availability.<br />

Contact the<br />

Laboratory<br />

3 working<br />

days<br />

Referral Laboratories:<br />

Special Haematology (page 1 of 3)<br />

For Nucleotides, PF1.2 and TAT (Thrombin<br />

antithrombin complex)<br />

Haemostasis Research Unit,<br />

Department of Haematology<br />

<strong>University</strong> <strong>College</strong> <strong>London</strong> <strong>Hospitals</strong><br />

1 st Floor, 51 Chenies Mews<br />

<strong>London</strong> WC1E 6HX<br />

For VWF Multimers<br />

Haemophilia Centre and Thrombosis Unit,<br />

Ground Floor<br />

Royal Free Hospital<br />

Pond Street<br />

<strong>London</strong> NW3 2QG<br />

For Factor V Leiden, Prothrombin Gene<br />

Mutation and MTHFR Mutation<br />

TDL Genetics<br />

3 rd Floor<br />

60 Whitfield Street<br />

<strong>London</strong> W1T 4EU<br />

2 nd Floor, 60 Whitfield St <strong>London</strong> W1T 4EU Hours: 09.00 -17.15 Monday – Friday 0203 447 8533 or x78533<br />

HAEM-PD-UserHbook V8 Haematology and Blood Transfusion User Handbook Page 25 of 38<br />

Authors: Karen Orfinada (Senior Biomedical Scientist)<br />

Sally McDonald (Senior Biomedical Scientist) Authorised by: Dave Barnett Review Date: August 2015

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