haematology users' handbook - University College London Hospitals
haematology users' handbook - University College London Hospitals
haematology users' handbook - University College London Hospitals
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Haemostasis (page 6 of 6)<br />
Test Specimen type Key Factors<br />
affecting<br />
tests<br />
Notes<br />
Referenc<br />
e Range<br />
Out of<br />
hours<br />
service<br />
Time Limit<br />
for<br />
requesting<br />
additional<br />
tests from<br />
time of<br />
venesection<br />
Turnaround<br />
time from<br />
receipt of<br />
sample (in<br />
working<br />
days for<br />
non urgent<br />
requests)<br />
Thrombophilia screen<br />
Antithrombin,<br />
Protein C,<br />
Protein S,<br />
Lupus Anticoagulant,<br />
Cardiolipin Antibodies,<br />
Factor V Leiden,<br />
Prothrombin Gene<br />
Mutation, MTHFR<br />
mutation.<br />
Also Factor VII and X<br />
assays when patients<br />
are on warfarin.<br />
4 x 4.5ml<br />
Sodium<br />
Citrated<br />
samples<br />
+<br />
1 x 5ml SST<br />
sample<br />
+<br />
1 x 4.5ml<br />
EDTA<br />
Delayed<br />
receipt of<br />
sample.<br />
Plasma must<br />
be processed<br />
within 5<br />
hours of<br />
venesection.<br />
Warfarin and<br />
Heparin<br />
Acute illness<br />
may affect<br />
results of<br />
some tests<br />
These tests require authorisation<br />
unless the patient is a Haematology,<br />
NHNN or HASU patient: for all other<br />
patients, please contact the<br />
Haemostasis or Haematology SpR<br />
(bleep 7044 or 7000) for authorisation<br />
before taking samples.<br />
These tests can be requested<br />
individually.<br />
Samples for Factor V Leiden, MTHFR<br />
and Prothrombin Gene Mutation are<br />
sent from Haemostasis, UCLH to TDL<br />
Genetics<br />
Contact<br />
the<br />
laboratory<br />
Antithrombin,<br />
Protein C<br />
and Protein S<br />
only, by<br />
agreement<br />
with the<br />
Haematology<br />
Consultant<br />
on call and<br />
subject to<br />
staff<br />
availability.<br />
Contact the<br />
Laboratory<br />
3 working<br />
days<br />
Referral Laboratories:<br />
Special Haematology (page 1 of 3)<br />
For Nucleotides, PF1.2 and TAT (Thrombin<br />
antithrombin complex)<br />
Haemostasis Research Unit,<br />
Department of Haematology<br />
<strong>University</strong> <strong>College</strong> <strong>London</strong> <strong>Hospitals</strong><br />
1 st Floor, 51 Chenies Mews<br />
<strong>London</strong> WC1E 6HX<br />
For VWF Multimers<br />
Haemophilia Centre and Thrombosis Unit,<br />
Ground Floor<br />
Royal Free Hospital<br />
Pond Street<br />
<strong>London</strong> NW3 2QG<br />
For Factor V Leiden, Prothrombin Gene<br />
Mutation and MTHFR Mutation<br />
TDL Genetics<br />
3 rd Floor<br />
60 Whitfield Street<br />
<strong>London</strong> W1T 4EU<br />
2 nd Floor, 60 Whitfield St <strong>London</strong> W1T 4EU Hours: 09.00 -17.15 Monday – Friday 0203 447 8533 or x78533<br />
HAEM-PD-UserHbook V8 Haematology and Blood Transfusion User Handbook Page 25 of 38<br />
Authors: Karen Orfinada (Senior Biomedical Scientist)<br />
Sally McDonald (Senior Biomedical Scientist) Authorised by: Dave Barnett Review Date: August 2015