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Course Book - University of Sulaimani

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2011<br />

2012<br />

<strong>University</strong><br />

Of<br />

<strong>Sulaimani</strong><br />

School<br />

Of<br />

PRACTICAL HISTOLOGY<br />

COURSE BOOK<br />

[A short review <strong>of</strong> the key laboratory titles and outlines used as a student guide]<br />

Science<br />

Biology Dept.<br />

3 rd Year Biology<br />

1 st Semester 2011-2012


Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 1


<strong>Course</strong> title<br />

Histology<br />

lecturers in charge Assist. lecturer: Sirwan Mustafa Mohammed<br />

Assist. lecturer: Shilan Muhammad Ra'uf<br />

Dept/ College Biology Science<br />

Contact details Email: sirwan.mohammed@univsul.net<br />

shilan.rauf@univsul.net<br />

Lecturer’s Code 41211337<br />

Coordinator’s<br />

name<br />

Sirwan M. Mohammed<br />

sirwan75@gmail.com<br />

‌<strong>Course</strong> overview:<br />

Histology is the study <strong>of</strong> microscopic anatomy dealing with the structures <strong>of</strong> cells,<br />

tissue and organs in relation to their functions.<br />

The first part <strong>of</strong> the course deals with basic tissues (a collection <strong>of</strong> similar cells and<br />

the extracellular matrices surrounding them): epithelium; connective tissues<br />

(proper, specialized- blood, bone and cartilage); muscles; and nerves.<br />

The second part <strong>of</strong> the course deals with organs, systemic arrangement <strong>of</strong> tissues<br />

performing a specific function, as <strong>of</strong> cardiovascular system, integumentary system,<br />

respiratory system, digestive system ( GIT and associated glands), endocrine<br />

system, urinary system, female reproductive system, male reproductive system and<br />

finally, the sense organs. The course deals mainly with the structural aspects <strong>of</strong><br />

cells, tissues and organs. It also covers the basic functions <strong>of</strong> these structures.<br />

Note: All lectures are in power point format only, illustrated and sometimes<br />

animated and contain explanatory diagrams and videos.<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 2


<strong>Course</strong> Objectives:<br />

The purpose <strong>of</strong> histology course is to teach students how to identify various types<br />

<strong>of</strong> cells in standard prepared histological sections and to identify a variety <strong>of</strong> normal<br />

tissues.<br />

At the end <strong>of</strong> the histology course, the student is expected to be able to:<br />

1-Understand the histological structure <strong>of</strong> each <strong>of</strong> the organs <strong>of</strong> the body systems.<br />

2-Identify cells, tissues and organs <strong>of</strong> the body systems.<br />

3-Understand the structural and functional relationships <strong>of</strong> the cells, tissues and<br />

organs <strong>of</strong> the body systems.<br />

<strong>Course</strong> Reading List and References‌<br />

Main references<br />

1- JUNQUEIRA'S Basic Histology TEXT & ATLAS, by Anthony L. Mescher,<br />

12th Edition (©2010) (electronic book)<br />

2- Luiz Carlos Junqueira and Jose Carneiro (©2005).Basic Histology, text and<br />

atlas, 11th ed.; International edition. (electronic book)<br />

3- Victor p. Eroschenko. (©2005). diFiore’s Atlas <strong>of</strong> Histology with functional<br />

correlations,10th ed.;Lippincott Williams & Wilkins. (available in the lab)<br />

4- Burkitt H.G. ,Young B. and Heath J.W. (©2001). Wheater’s Functional<br />

Histology, a text and Coulor atlas.4 th ed.;Churchill Livingstone. (electronic book)<br />

5- Victor p. Eroschenko. (©1993). diFiore’s Atlas <strong>of</strong> Histology with functional<br />

correlations,7th ed. (Egyptian Edition);Elias Modern press. (electronic book)<br />

Useful References<br />

- Color Textbook <strong>of</strong> Histology, Gartner & Hiatt, 3 rd ed (©2007) (electronic book)<br />

-http://www.histology-world.com<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 3


Subject 1: Epithelial Tissue<br />

Assist. Instructor‌: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: student should be able to:<br />

1. Describe the characteristic features and functions <strong>of</strong> epithelial tissue.<br />

2. List the classification <strong>of</strong> types <strong>of</strong> epithelia and know example <strong>of</strong> location within<br />

the body.<br />

Scientific contents:<br />

1. General characteristics and functions <strong>of</strong> epithelium.<br />

2. Classification (different types and sites <strong>of</strong> each type) <strong>of</strong> epithelium.<br />

Subject 2: Connective Tissue Proper<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: students should be able to distinguish the different types <strong>of</strong> connective<br />

tissue, understand the role <strong>of</strong> their cellular, fibrous and ground substance<br />

components.<br />

Scientific contents:<br />

1-Definition and Function <strong>of</strong> connective tissue proper.<br />

2- Components <strong>of</strong> connective tissue.<br />

3- Classification & types <strong>of</strong> connective tissue proper and sites <strong>of</strong> each type.<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 4


Subject 3: Bone and Cartilage<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: student should be able to:<br />

1-Identify and describe the histological structure and location <strong>of</strong> various types <strong>of</strong><br />

cartilage (hyaline, elastic and fibrocartilage).<br />

2- Identify and describe the histological structure and location <strong>of</strong> various types <strong>of</strong><br />

bone (spongy and compact).<br />

Scientific contents:<br />

1- Components, functions, types (hyaline, elastic, and fibro cartilage),<br />

locations, cells <strong>of</strong> cartilage (chondroblast and chondrocyte).<br />

2- Structure, types (compact and spongy bone), cells <strong>of</strong> bone (osteoblast,<br />

osteoclast, and osteocyte).<br />

Subject 4: Muscular Tissue<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: to be able to recognize the structure and functions <strong>of</strong> the 3 types <strong>of</strong><br />

muscles (skeletal, cardiac, and smooth) and distinguishing them from connective<br />

tissue, they should also aim to identify the connective tissue arrangements <strong>of</strong><br />

skeletal muscle.<br />

Scientific contents:<br />

1- Microscopic features <strong>of</strong> skeletal muscle, cardiac muscle, and smooth muscle.<br />

2-Skeletal muscle organization.<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 5


Subject 5: Nerve Tissue I<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: students should understand:<br />

1- Classify the nervous system.<br />

2- Identify the different parts <strong>of</strong> the peripheral nervous system.<br />

3-Classify neurons<br />

4- Know the structure and type <strong>of</strong> ganglion.<br />

5-Classify synapse<br />

6-Neuroglial cells.<br />

7- Nerve endings.<br />

Scientific contents:<br />

1-Basic structure <strong>of</strong> nerve tissue.<br />

2-Neurons (1)The classification <strong>of</strong> neuron (2)The structure and function <strong>of</strong><br />

neuron.<br />

3-Synapse (definition, types).<br />

4-Neuroglia (function, classification).<br />

5- Nerve fiber (Definition, types: myelinated nerve fiber and unmyelinated nerve<br />

fiber, and structure <strong>of</strong> myelinated nerve fiber).<br />

6-nerve endings (definition, types).<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 6


Subject 6: Nerve Tissue II<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives:<br />

1-Be able to identify parts <strong>of</strong> central nervous system {brain(cerebellum, and<br />

cerebrum), and spinal cord}<br />

2-Identify white vs. gray matter in the spinal cord, cerebellum, and cerebrum.<br />

3-Be able to recognize the cortex and medullary layers <strong>of</strong> cerebrum and cerebellum.<br />

Scientific contents:<br />

Central nervous system (CNS)<br />

• Brain (cerebellum & cerebrum)<br />

• Spinal cord<br />

Subject 7: Cardiovascular system<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: Students should be able to:<br />

1-Describe the histological structure <strong>of</strong> the heart wall.<br />

2- Classify arteries and veins, identify and describe their histological structure and<br />

changes which occur in their three tunicae at different levels and relate these<br />

changes to their function.<br />

3-Describe and identify different types <strong>of</strong> capillaries including sinusoids and relate<br />

their structure to the function.<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 7


Scientific contents:<br />

1-Histological structure <strong>of</strong> the heart wall.<br />

2- Classification <strong>of</strong> arteries and veins; their structural modifications in relation to<br />

their functions.<br />

3- Different varieties <strong>of</strong> capillaries and blood sinusoids.<br />

Subject 8: Integumentary system<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: to recognize the structural elements <strong>of</strong> the skin which are responsible<br />

for their functions, types <strong>of</strong> skin and their layers, types <strong>of</strong> skin appendages.<br />

Scientific contents:<br />

1- Types & sites <strong>of</strong> skin<br />

-Histology <strong>of</strong> thick non-hairy skin<br />

-Histology <strong>of</strong> thin hairy skin<br />

4-Skin appendages (hair and hair follicles, nail, sebaceous gland, and sweat gland).<br />

Subject 9: Endocrine system<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: students should be able to:<br />

1-Recognize and distinguish the various endocrine organs (thyroid, parathyroid,<br />

adrenal and pituitary).<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 8


2-Identify the parts <strong>of</strong> the pituitary gland, name the cell types that produce the<br />

various hormones <strong>of</strong> the anterior pituitary, and know whether they are acidophils or<br />

basophils.<br />

3- Describe structures <strong>of</strong> thyroid gland, Recognize the parathyroid gland in<br />

histological section, and within the gland identify the chief cells (source <strong>of</strong><br />

parathyroid hormone) and oxyphil cells.<br />

4- Recognize the zones <strong>of</strong> the adrenal cortex (that produce aldosterone and cortisol)<br />

and medulla.<br />

Scientific contents:<br />

1. Definition<br />

2.Pituitary gland<br />

3.Thyroid , parathyroid gland<br />

4.Adrenal gland<br />

Subject 10: Urinary system<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives: students should be able to:<br />

1- Identify parts and functions <strong>of</strong> the urinary system<br />

3- Describe parts <strong>of</strong> the uriniferous tubules and the nephron.<br />

4- Juxtaglomerular apparatus and its function.<br />

5- Renal corpuscles and tubules and distinguishing between them in sections.<br />

6- Describe the wall <strong>of</strong> ureter, urinary bladder, and urethra.<br />

Scientific contents:<br />

1-kidneys overview<br />

2-Nephron structure<br />

a-Renal corpuscles (glomerulus)<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 9


- Renal tubules (Proximal convoluted tubule, Loop <strong>of</strong> Henle, distal convoluted<br />

tubule, and collecting tubules).<br />

3-urinary tracts (ureter, urinary bladder, and urethra).<br />

Subject 11: Digestive system I<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives:<br />

1-Review and understand the basic components and gross anatomy <strong>of</strong> the digestive<br />

system.<br />

2-Describe the histological components <strong>of</strong> the different parts <strong>of</strong> the upper<br />

alimentary tract with their functional correlations.<br />

Scientific contents:<br />

1-Overview & gross anatomy <strong>of</strong> digestive system.<br />

2-Oral cavity (lips, tongue, oral mucosa, and salivary glands).<br />

3-Gastrointestinal tract (esophagus, stomach).<br />

Subject 12: Digestive system II<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives:<br />

1-To illustrate the gross anatomy <strong>of</strong> the lower alimentary tract starting from the<br />

small intestine extending to the anus.<br />

2- To give the student a comprehensive understanding <strong>of</strong> the histological<br />

components <strong>of</strong> the lower alimentary tract with their physiological roles.<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 10


Scientific contents:<br />

1-Small intestine anatomy (duodenum, jejunum, and ileum).<br />

2-Large intestine anatomy (caecum, ascending colon, transverse colon, descending<br />

colon, sigmoid colon, rectum, anus).<br />

Subject 13: Accessory Digestive Glands<br />

Assist. Instructor: Shilan Muhammed Ra’uf<br />

Assist. Instructor‌: Sirwan Mustafa Mohammed<br />

Objectives:<br />

1- To give the details <strong>of</strong> the digestive associated organs including, their<br />

location, types and gross anatomy.<br />

2- To show a comprehensive understanding <strong>of</strong> the histological components <strong>of</strong><br />

the digestive associated glands in addition to their crucial role in the<br />

digestion process.<br />

Scientific contents:<br />

1- Pancreas<br />

2- Liver<br />

3- Gall bladder<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 11


Syllabus<br />

No. Title <strong>of</strong> the Subject Lecture’s name<br />

1 Epithelial Tissue<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

2<br />

Connective Tissue<br />

Proper<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

3 Bone & Cartilage<br />

4 Muscular Tissue<br />

5 Nervous Tissue I<br />

6 Nervous Tissue II<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

7 1 st Exam (120 points)<br />

8 Cardiovascular System<br />

9 Integumentary System<br />

10 Endocrine System<br />

11 Urinary System<br />

12 Digestive System I<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 12


13 Digestive System II<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

14<br />

Accessory Digestive<br />

Glands<br />

Shilan Muhammed Ra’uf<br />

Sirwan Mustafa Mohammed<br />

15 2nd Exam (120 points)<br />

Evaluation (Exams):<br />

Two examinations will be given during the course.<br />

Final exams will be based on materials given in the labs, your grade will be<br />

determined through two (2) laboratory practical exams.<br />

The topics to be covered on each exam are indicated in the lab schedule above.<br />

The exam will consist <strong>of</strong> identify cells, layers, tissues, identify the pointed part,<br />

organs and their details from microscope slides and digital images <strong>of</strong> power points<br />

slides displayed by data show.<br />

Practical exam consists <strong>of</strong> 12 questions, each question worth 10 points and should<br />

be answered within 2 minutes (30 mins.duration).<br />

Lab Practical Quizzes:<br />

Each Laboratory Quiz (10 points) will be based mainly on the material studied in<br />

the previous week's lab. At the end <strong>of</strong> the semester when final grades are being<br />

determined, one quiz grades <strong>of</strong> 0 for each student may not be counted toward the<br />

final grade.<br />

Laboratory Quiz will be given during the first 5 minutes <strong>of</strong> each laboratory time.<br />

Grading:<br />

Final grades will be assigned as follows:<br />

1 st practical exam 120 points<br />

2 nd practical exam 120 points<br />

Final grade 12%<br />

Practical quizzes 100 points Final grade 3%<br />

Total 15%<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 13


General Notes:<br />

Use <strong>of</strong> cell phones is prohibited during exams. Be sure that you have your cell<br />

phones turned <strong>of</strong>f and stored before coming to class. Use <strong>of</strong> a cell phone during an<br />

exam is grounds for receiving a failing grade for the exam.<br />

No exam will be dropped. Makeup exams will only be available under<br />

extraordinary circumstances. If you miss an exam without prior arrangement and<br />

fail to notify me within one day <strong>of</strong> the exam time, you will receive a zero for the<br />

missed exam.<br />

Examples <strong>of</strong> types <strong>of</strong> questions:<br />

Answer:<br />

a- Loose (areolar) connective tissue<br />

b- Elastic fiber<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 14


Answer:<br />

a- hyaline cartilage<br />

b- trachea<br />

Answer:<br />

Q3// a- Identify the section<br />

b- Write 2 important feature <strong>of</strong> it<br />

a- dorsal root ganglia<br />

b- (1.nucleus centrally located<br />

2. The cell bodies are <strong>of</strong> pseudounipolar<br />

type)<br />

Note: a complete exam sample is found on the course web site, to download it click on the<br />

exam sample below:<br />

Exam Sample<br />

Practical Histology <strong>Course</strong> <strong>Book</strong> .UOS 2011 15

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