The PiTT-CMU MSTP NewSleTTer - University of Pittsburgh :: MSTP

New MSTP Student Publications through September 2010
Kaczorowski, D.J., Afrazi, A., Scott, M.J., Kwak, J.H., Gill, R., Edmonds, R.D., Liu, Y.,
Fan, J., and T.R. Billiar. (2010). Pivotal Advance: The pattern recognition receptor
ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor
B synthesis by the macrophage through distinct but overlapping mechanisms. J
Leukoc Biol.Oct; 88(4):609-18. [PMID: 20413727]
Richardson, W.M., Sodhi, C.P., Russo, A., Siggers, R.H., Afrazi, A., Gribar, S.C.,
Neal, M.D., Dai, S., Prindle, T. Jr, Branca, M., Ma, C., Ozolek, J., Hackam DJ.
(2010). Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4
signaling in the intestinal epithelium. Gastroenterology. Sep; 139(3):904-17, 917.
e1-6. [PMID: 20580721]
Bales, J.W., Ma, X., Yan, H.Q., Jenkins, L.W., and C.E. Dixon. (2010). Alterations in
calcineurin subunit B isoform expression in rat hippocampus following a traumatic
brain injury. Brain Res. Oct 28; 1358:211-20. [PMID: 20713027]
Bridges, J.P., Ikegami, M., Brilli, L.L., Chen, X., Mason, R.J., and J.M. Shannon.
(2010). LPCAT1 regulates surfactant phospholipid synthesis and is required
for transitioning to air breathing in mice. J. Clin. Invest. May 3; 120(5):1736-48.
[PMID: 20407208]
Chan, V., Starr, P.A., and R.S. Turner. (2010). Bursts and oscillations as independent
properties of neural activity in the parkinsonian globus pallidus internus. Neurobiol.
Dis. Aug 18 [Epub ahead of print; PMID: 20727974]
Chao, Y.*, Shepard, C.R.*, and A. Wells. (2010). Breast carcinoma cells re-express
E-cadherin during mesenchymal to epithelial reverting transition. Mol Cancer. Jul
7; 9(1):179. [PMID: 20609236]
Rajagopalan, M.S., Stone, B., Rwigema, J.C., Salimi, U., Epperly M.W., Goff, J.,
Franicola, D., Dixon, T., Cao, S., Zhang, X., Buchholz, B.M., Bauer, A.J., Choi,
S., Bakkenist, C., Wang, H., and J.S. Greenberger. (2010). Intraesophageal
Manganese Superoxide Dismutase-Plasmid Liposomes Ameliorates Novel Total-
Body and Thoracic Radiation Sensitivity of NOS1(-/-) Mice. Radiat Res. Sep;
174(3):297-312. [PMID: 20726721]
White, J.S., Choi, S., and C.J. Bakkenist. (2010). Transient ATM kinase inhibition
disrupts DNA damage induced sister chromatid exchange. Sci Signal. Jun 1;
3(124):ra44. [PMID: 20516478]
Choi, S., Gamper, A.M., White, J.S., and C.J. Bakkenist. (2010). Inhibition of ATM
kinase activity does not phenocopy ATM protein disruption: implications for the
clinical utility of ATM kinase inhibitors. Cell Cycle. Oct 15; 9(20):4052-7. [PMID:
20953138]
Frank, G.M.*, Divito, S.J.*, Maker, D.M., Xu, M., and R.L. Hendricks. (2010). A novel
p40-independent function of IL-12p35 is required for progression and maintenance
of herpes stromal keratitis. Invest Ophthalmol Vis Sci. Jul;51(7):3591-8. [PMID:
20207959] *Co-first authors
Divito, S.J., Wang, Z., Shufesky, W.J., Liu, Q, Tkacheva, O.A., Montecalvo, A., Erdos,
G., Larregina, A.T., and A.E.Morelli. (2010). Endogenous dendritic cells mediate
the effects of intravenously injected therapeutic immunosuppressive dendritic cells
in transplantation. Blood. Oct 14;116(15):2694-705. [PMID: 20576812]
Divito, S.J. and L.K. Ferris. (2010). Advances and short-comings in the early detection
of melanoma. Melanoma Res. Dec; 20(6):450-8. [PMID: 20856147]
Marenco, S., Savostyanova, A., van der Veen, J.W., Geramita, M., Stern, A., Barnett,
A.S., Kolachana, B., Radulescu, E., Zhang, F., Callicott, J.H., Straub, R.E., Shen,
J. and D.R. Weinberger. (2010). Genetic modulation of GABA levels in the anterior
cingulate cortex by GAD1 and COMT. Neuropsychopharmacology. Jul;35(8):1708-
17. [PMID: 20357758]
Glorioso, C., Oh, S., Duillard, G. and E. Sibille. (2010). Brain molecular aging, promotion
of neurological disease and modulation by Sirtuin5 longevity gene polymorphism.
Neurobiol Dis. Sep 29. [Epub ahead of print; PMID: 20887790]
Wang, L, Gordon, R.A., Huynh, L., Su, X., Park Min, K.H., Han, J., Arthur, J.S., Kalliolias,
G.D., and L.B. Ivashkiv. (2010). Indirect inhibition of Toll-like receptor and
type I interferon responses by ITAM-coupled receptors and integrins. Immunity.
Apr 23; 32(4):518-30. [PMID: 20362473]
Gupta, A.S., van der Meer, M.A.A., Touretzky, D.S., and A.D. Redish. (2010). Hippocampal
replay is not a simple function of experience. Neuron. Mar 11; 65(5):695-
705. [PMID: 20223204]
Haldar, M., Hedberg, M.L., Hockin, M.F., and M.R. Capecchi. (2009). A CreER based
random induction strategy for modeling translocation-associated sarcomas in mice.
Cancer Res. Apr 15; 69 (8):3657-64. [PMID: 19351831]
Marcu, J.P., Christian, R.T., Lau, D., Zielinski, A.J., Horowitz, M.P., Lee, J., Pakdel, A.,
Allison, J., Limbad, C., Moore, D.H., Yount, G.L., Desprez, P.Y., and S.D. McAllister.
(2010). Cannabidiol enhances the inhibitory effects of Δ9-tetrahydrocannabinol
on human glioblastoma cell proliferation and survival. Mol Cancer Ther. Jan;
9(1):180-9. [PMID: 20053780]
Horowitz, M.P. and J.T. Greenamyre. (2010). Mitochondrial iron metabolism and
its role in neurodegeneration. J Alzheimer’s Dis. 20 Suppl. 2: S551-68. [PMID:
20463401]
Horowitz, M.P. and J.T. Greenamyre. (2010). Gene-environment interactions in Parkinson’s
disease: The importance of animal modeling. Clin Pharmacol and Ther.
Oct; 88(4):467-74. [PMID: 20811350]
Bosch, J.J., Iheagwara, U.K., Reid, S., Srivastava, M.K., Wolf, J., Lotem, M., Ksander,
B.R., and S. Ostrand-Rosenberg. (2010). Uveal melanoma cell-based vaccines
express MHC II molecules that traffic via the endocytic and secretory pathways
and activate CD8(+) cytotoxic, tumor-specific T cells. Cancer Immunol Immunother.
Jan; 59(1):103-12. [PMID: 19557412]
Johnson, C.A. Jr., Vandenberghe, S., Daly, A.R., Woolley, J.R., Snyder, S.T., Verkaik,
J.E., Ye, S.H., Borovetz, H.S., Antaki, J.F., Wearden, P.D., Kameneva, M.V., and
W.R. Wagner. (2010). Biocompatibility assessment of the first generation Pedia-
FlowTM Pediatric Ventricular Assist Device. Artif Organs. Jul 9 [Epub ahead of
print; PMID: 20626737]
Ye, S.Ho., Johnson, C.A. Jr., Woolley, J.R., Murata, H., Gamble, L.J., Ihsihara, K., and
W.R. Wagner. (2010). Simple surface modification of a titanium alloy with silanated
zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity.
Colloids Surf B Biointerfaces. Sep 1; 79(2):357-64. [PMID: 20547042]
Zhong, Z., Chang, S.A., Kalinowski, A., Wilson, K.L., and K.N. Dahl. (2010). Stabilization
of the spectrin-like domains of nesprin-1alpha by the evolutionarily conserved
“adaptive” domain. Cell Mol Bioeng. Jun 1; 3(2):139-150. [PMID: 20563238]
Dahl, K.N., Kalinowski, A., and K. Pekkan. (2010). Mechanobiology and the microcirculation:
cellular, nuclear and fluid dynamics. Microcirculation. Apr; 17(3):179-91.
[PMID: 20374482]
Kliment, C.R., and T.D. Oury. (2010). Oxidative stress, extracellular matrix targets,
and idiopathic pulmonary fibrosis. Free Radic Biol Med. Sep 1; 49(5):707-17.
[PMID: 20452419]
Houghton, A.M., Rzymkiewicz, D.M., Ji, H., Gregory, A.D., Egea, E.E., Metz, H.E.,
Stolz, D.B., Land, S.R., Marconcini, L.A., Kliment, C.R., Jenkins, K.M., Beaulieu,
K.A., Mouded, M., Frank, S.J., Wong, K.K., and S.D. Shapiro. (2010). Neutrophil
elastase mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med.
Feb; 16(2):219-23. [PMID: 20081861]
Koenitzer, J.R., and B.A. Freeman. (2010). Redox signaling in inflammation: interactions
of endogenous electrophiles and mitochondria in cardiovascular disease. Ann
NY Acad Sci. Aug; 1203:45-52. [PMID: 20716282]
Polk, A.A., Maul, T.M., McKeel, D.T., Snyder, T.A., Lehocky, C.A., Pitt, B., Stolz, D.B.,
Federspiel, W.J., and W.R. Wagner. (2010). A biohybrid artificial lung prototype
with active mixing of endothelialized microporous hollow fibers. Biotechnol Bioeng.
Jun 15; 106(3):490-500. [PMID: 20091735]
Tottey, S., Corselli, M., Jeffries, E.M., Londono, R., Peault, B., and S.F. Badylak. (2010).
Extracellular matrix degradation products and low oxygen conditions enhance the
regenerative potential of perivascular stem cells. Tissue Eng Part A. Sep 6. [Epub
ahead of print; PMID: 20653348]
Ho, A.W., Shen, F., Conti, H.R., Patel, N., Childs, E.E., Peterson, A.C., Hernandez-
Santos, N., Kolls, J.K., Kane, L.P., Ouyang, W., and S.L. Gaffen. (2010). IL-17RC
Is required for immune signaling via an extended SEF/IL-17R signaling domain in
the cytoplasmic tail. J Immunol. Jul 15; 185(2):1063-70. [PMID: 20554964]
Ruffner, M.A., and P.D. Robbins. (2010). Dendritic cells transduced to express IL-4
prevent diabetes onset in both normoglycemic and prediabetic nonobese diabetic
mice. PLoS ONE. Jul 29; 5(7):e11848. [PMID: 20686610]
Sanders, J.L., Cappola, A.R., Arnold, A.M., Boudreau, R.M., Chaves, P.H., Robins,
J., Cushman, M., and A.B. Newman. (2010). Concurrent change in dehydroepiandrosterone
sulfate (DHEAS) and functional performance in the oldest old: results
from the Cardiovascular Health Study All Stars Study. J Gerontol A Biol Med Sci.
Sep; 65(9):976-81. [PMID: 20466773]
Orchard, T.J., Secrest, A.M., Miller, R.G., and T. Costacou. (2010). In the absence
of renal disease, 20-year mortality risk in type 1 diabetes is comparable to that
of the general population: A report from the Pittsburgh Epidemiology of Diabetes
Complications Study. Diabetologia. Nov; 53(11):2312-9. [PMID: 20665208]
Secrest, A.M., Becker, D.J., Kelsey, S.F., LaPorte, R.E., and T.J. Orchard. (2010).
Cause specific mortality trends in a large population-based cohort with longstanding
childhood-onset type 1 diabetes: The Allegheny County Type 1 Diabetes Registry.
Diabetes. Aug 25. [Epub ahead of print; PMID: 20739685]
Stetten, G., Horvath, S., Galeotti, J., Shukla, G., and B. Chapman, (2010). Image
segmentation using the student’s ttest on adjacent spherical populations of pixels.”
SPIE Medical Imaging, paper #7623-125, poster presentation 12/14-15/2010.
Galeotti, J., Sajjad, A., Wang, B., Kagemann, L., Shukla, G., Siegel, M., Wu, B.,
Klatzky, R., Wollstein, G., Schuman, J., and G. Stetten. (2010). The OCT penlight:
In-situ image guidance for microsurgery. SPIE Medical Imaging, paper #7625-1,
oral presentation 12/14/2010.
Svilar, D., Goellner, E.M., Almeida, K.H., and R.W Sobol. (2010). Base Excision Repair
and lesion-dependent sub-pathways for repair of oxidative DNA damage. Antioxid
Redox Signal. Oct 28. [Epub ahead of print; PMID: 20649466]
Drowley, L., Okada, M., Beckman, S., Vella, J., Keller, B., Tobita, K., and J. Huard.
(2010). Cellular antioxidant levels influence muscle stem cell therapy. Mol Ther.
Oct; 18(10):1865-73. [PMID: 20664528]
Stetler, R.A., Gao, Y., Zukin, R.S., Vosler, P.S., Zhang, L., Zhang, F., Cao, G., Bennett,
M.V.L. and J. Chen. (2010). Apurinic/apyrimidinic endonuclease APE1 is required
for PACAP-induced neuroprotection against global cerebral ischemia. Proc Natl
Acad Sci. Feb 16; 107(7) 3204-9. [PMID: 20133634]
Romero, G., Sneddon, W.B., Yang, Y., Wheeler, D.S., Blair, H.C., and P.A. Friedman.
(2010). Parathyroid hormone receptor directly interacts with dishevelled
to regulate beta-Catenin signaling and osteoclastogenesis. J Biol Chem. May 7;
285(19):14756-63. [PMID: 20212039]
Wheeler, D.S., Barrick, S.R., Grubisha, M.J., Brufsky, A.M., Friedman, P.A., and G.
Romero. (2010). Direct interaction between NHERF1 and Frizzled regulates betacatenin
signaling. Oncogene. Aug 30. [Epub ahead of print; PMID: 20802536]
Jiao, J.A., Kelly, A.B., Marzec, U.M., Nieves, E., Acevedo, J., Burkhardt, M., Edwards,
A., Zhu, X.Y., Chavaillaz, P.A., Wong, A., Wong, J.L., Egan, J.O., Taylor, D., Rhode,
P.R., and H.C. Wong. (2010). Inhibition of acute vascular thrombosis in chimpanzees
by an anti-human tissue factor antibody targeting the factor X binding site.
Thromb Haemost, Jan; 103(1):224-33. [PMID: 20062929]
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