von Willebrand Disease Presentation - Virginia Commonwealth ...
von Willebrand Disease Presentation - Virginia Commonwealth ...
von Willebrand Disease Presentation - Virginia Commonwealth ...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Function of <strong>von</strong> <strong>Willebrand</strong> Factor in Clotting<br />
Process<br />
• vWF is a glue-like protein needed for platelet plug<br />
formation<br />
• Major functions<br />
– Serves as a bridge between platelets and injury<br />
sites in the blood vessel<br />
– Carries and protects one of the clotting factors<br />
(factor 8) in the blood that helps make the fibrin<br />
strands that strengthen the platelet plug<br />
Kleinert D et al. JOGNN. 1997;26:271-276.<br />
Ginsburg D, Bowie EJW. Blood. 1992;79:2507-2519.
Change language