von Willebrand Disease Presentation - Virginia Commonwealth ...

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Prevalence of vWD • Most common inherited bleeding disorder • Estimated to affect ~1% of the population (mostly type 1) • Males and females of all races may be affected • May be diagnosed at any age • Symptoms generally mild and may not require frequent treatment with type 1 Kleinert D et al. JOGNN. 1997;26:271-276. Ewenstein BM. Annu Rev Med. 1997;48:525-542.
Types of von Willebrand Disease • Three different types of von Willebrand Disease: Type 1, 2 and 3 • The severity of the bleeding problem will depend on the type of von Willebrand Disease
Page 1 and 2: Von Willebrand Disease: When is a
Page 3 and 4: Objectives • To review the clinic
Page 5 and 6: von Willebrand Disease (vWD) A pers
Page 7 and 8: Clotting Illustration William J. A
Page 9: Platelet Plug Formation • Platele
Page 14 and 15: Type 1 vWD • Most common type; in
Page 16: • Rare Type 3 vWD • Quantitativ
Page 19 and 20: vWD: Sites of Bleeding Mucous membr
Page 21 and 22: Symptoms of vWD • Bleeding after
Page 23 and 24: Characteristics of Menorrhagia •
Page 27 and 28: Causes of variance in Von Willebran
Page 29 and 30: Inheritance of vWD • Gene is carr
Page 31 and 32: Inheritance Pattern by Type of von
Page 33 and 34: Diagnosis of vWD • Personal and f
Page 35 and 36: Suggested Questions for Screening P
Page 37 and 38: Suggested Questions for Screening P
Page 39 and 40: Treatment of vWD • Treatment deci
Page 41 and 42: Intranasal Desmopressin: Stimate
Page 43 and 44: Side-effects of Stimate • Fluid r
Page 45 and 46: Amicar (aminocaproic acid) • Oral
Page 47 and 48: Hormonal Therapy for vWD • Treatm
Page 49 and 50: Treatment With vWF Concentrates (co
Page 51 and 52: Psychosocial Issues: Adolescent Wom
Page 53 and 54: Recommendations for Patients • Ha
Page 55 and 56: Summary • In VWD, you either have
Page 57 and 58: Summary • Treatments for VWD incl
Page 59 and 60: Referral for evaluation of VWD •
Page 61 and 62: Role of Hemophilia Treatment Center
Page 63:
Virginia Bleeding Disorders Program
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von Willebrand Disease Presentation - Virginia Commonwealth ...

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