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Apheresis: Basic Principles, Practical Considerations and

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<strong>Apheresis</strong>- Mechanism of Action<br />

•Large-bore intravenous catheter connected to a<br />

spinning centrifuge bowl<br />

•Whole blood is drawn from donor/patient into the<br />

centrifuge bowl<br />

•The more dense elements, namely the RBC, settle to<br />

the bottom with less dense<br />

elements such as WBC <strong>and</strong><br />

platelets overlying the RBC<br />

layer <strong>and</strong> finally, plasma at<br />

the very top.

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