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Urgent Warnings, Breakthrough Solutions, Second Edition

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continued from page 13<br />

lism advances, however, clinicians<br />

will learn to group patients into biometabolism<br />

classes and tissue-type<br />

groups to determine who will benefit<br />

from a specific drug and who will<br />

have adverse reactions. Use of biometabolism<br />

classes and tissue-type<br />

groups will be widespread by 2050<br />

and result in increased drug effectiveness,<br />

fewer negative drug reactions,<br />

and lower drug-treatment<br />

costs.<br />

“Understanding how the brain operates<br />

on an individual basis will<br />

permit society to match the individual<br />

to task performance, to individualize<br />

educational programs, and to<br />

identify and mitigate mental illness.”<br />

14. Tissue Engineering<br />

The creation of self-replicating biomaterials<br />

for healing wounds and<br />

bone fractures, including the combining<br />

of synthetic materials and<br />

structures with living cells, is another<br />

area of scientific exploration.<br />

Tissue engineering will revolutionize<br />

body and wound repair, organ transplantation,<br />

and surgery in general.<br />

New polymers that satisfy safety<br />

and effectiveness requirements are<br />

being researched and developed for<br />

many surgical uses, including tissue<br />

scaffolding, bone grafts, cartilage repair,<br />

tissue regeneration, wound repair,<br />

and tissue joining. Soon, artificial<br />

organs and body parts will be<br />

available for replacement surgery.<br />

Research programs are now under<br />

way to develop artificial ears, hearts,<br />

pancreases, lungs, kidneys, livers,<br />

and legs.<br />

15. Neurotechnology<br />

Neuroscientists have developed a<br />

set of scanners capable of determin-<br />

ing how and where the brain performs<br />

specific functions. The new<br />

brain-scanning and brain-mapping<br />

tools are opening up a whole new<br />

understanding of how humans think<br />

and act. Using them, researchers can<br />

observe brain activity, measure its<br />

intensity, chart the general pattern of<br />

brain operation, and identify the<br />

type of chemical reactions occurring<br />

in the brain.<br />

Brain-scanning technology will<br />

soon be upgraded by the use of<br />

atomic magnetometer sensors—a<br />

new magnetic sensor technology<br />

that uses cesium vapor as a sensing<br />

element. These devices are 100 times<br />

more sensitive and 1,000 times faster<br />

than present sensor elements. They<br />

will, with time, better discern how<br />

people think, how the brain performs<br />

tasks, how thought processes<br />

differ among individuals, and what<br />

those differences mean in relation to<br />

task performance and personality.<br />

The new knowledge of brain operation<br />

and its effects<br />

will be one of the<br />

major, socially transforming<br />

events of<br />

the twenty-first century.<br />

Understanding<br />

how the brain operates<br />

on an individual<br />

basis will permit<br />

society to match the<br />

individual to task<br />

performance, to individualize<br />

educational<br />

programs,<br />

and to identify and<br />

mitigate mental illness.<br />

16. Neuropharmacology<br />

We can now see the operation of<br />

the brain. We can also systematically<br />

study and measure the effects of nutrients,<br />

micronutrients, and drug<br />

treatments on the brain and on various<br />

mental conditions. This has led<br />

to the new science of neuropharmacology—the<br />

study of how we change<br />

the brain’s operation through the use<br />

of drugs, food, and other nutrients,<br />

micronutrients, and proteins. Over<br />

time, this field will apply knowledge<br />

of the brain’s biochemical operations<br />

to systematically treat mental disorders<br />

and mental conditions<br />

pharma ceutically, as well as enhance<br />

people’s natural mental abilities.<br />

17. Cellulose-to-Glucose<br />

Process<br />

One of the major goals of the biotech<br />

and chemical industry is the<br />

production of glucose, the principal<br />

food of many microorganisms, from<br />

cellulose. If cheap, plentiful glucose<br />

were available, microbes could be<br />

genetically engineered to make almost<br />

anything. An economical cellulose-to-glucose<br />

process would revolutionize<br />

the world’s chemical<br />

industries and allow the conversion<br />

of much agricultural cellulose-based<br />

waste into useful raw materials.<br />

18. Nanotechnology<br />

Instrumentation has begun to permit<br />

us to see and manipulate matter<br />

at a nano level—10 -6 to 10 -9 meter—<br />

the level of atoms and molecules.<br />

This has created the new field of<br />

nanotechnology. The ability to create<br />

smaller structures using modern<br />

chip-manufacturing technology will<br />

permit us to change and modify materials<br />

one atom or molecule at a<br />

time and to develop super-fine powders,<br />

quantum dots, and nanotubes.<br />

These capabilities have now started<br />

to shrink things into the “upper<br />

nano” range—a range that advancements<br />

in production technology will<br />

push us into over the next 10 to 15<br />

years. The scale of objects will continue<br />

to shrink, and some useful<br />

upper- nanoscale devices and phenomena<br />

will be developed and deployed.<br />

19.<br />

Chaos Theory and<br />

Complexity Models<br />

Our world is much more complex,<br />

interconnected, and dynamic than<br />

we once thought. New mathematical<br />

concepts are challenging the rationalized,<br />

deterministic, scientific<br />

models of the Industrial Age. The Industrial<br />

Age paradigm held that<br />

there is one best way to organize a<br />

given thing and that, in all cases, a<br />

given “rational” outcome is predetermined<br />

by nature. The new scientific<br />

paradigm will ultimately replace<br />

this older mentality.<br />

<strong>Urgent</strong> <strong>Warnings</strong>, <strong>Breakthrough</strong> <strong>Solutions</strong> 15

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