<strong>Molecular</strong> <strong>Neurobiology</strong> previous next Table of contents Section contents Home Exit D7 Huntington’s disease and other CNS disor<strong>de</strong>rs Group Lea<strong>de</strong>r: José Lucas Postdoctoral: Celia Cerrato Rivera Mª <strong>de</strong>l Rosario Fernán<strong>de</strong>z Fernán<strong>de</strong>z Owen Howard Cristina Tomás Zapico Predoctoral fellows: Raquel Gómez Sintes Zaira Ortega Llorente Research summary Staff Publications Other activities Technical Assistance: Desire Ruiz García Alicia Tomico García Stu<strong>de</strong>nts: Marta Fernán<strong>de</strong>z Nogales Enrique Gaban<strong>de</strong> Rodríguez Visiting scientist: Miguel Díaz Hernán<strong>de</strong>z Patents CBM 2007-2008
<strong>Molecular</strong> <strong>Neurobiology</strong> previous next Table of contents Section contents Home Exit D7 Huntington’s disease and other CNS disor<strong>de</strong>rs Research summary Staff Publications Other activities Patents Publications Gómez-Sintes, R., Hernán<strong>de</strong>z, F., Bortolozzi, A., Artigas, F., Avila, J., Zaratin, P., Gotteland, J.-P. and Lucas, J.J. (2007). Neuronal apoptosis and reversible motor <strong>de</strong>ficit in dominat-negative GSK-3 conditional transgenic mice. EMBO J. 26: 2743-2754. Engel, T., Lucas, J.J., Hernán<strong>de</strong>z, F., and Avila, J. (2007). A mouse mo<strong>de</strong>l to study tau pathology related with tau phosphorylation and assembly. J. Neurol. Sci. 257: 250-254. Hooper, C., Markevich, V., Killick, R., Schofield, E., An<strong>de</strong>rton, B., Rosenblum, K., Bliss, T., Engel, T., Hernan<strong>de</strong>z; F., Avila, J., Lucas, J.J., Stephenson, J. and Lovestone, S. (2007). Glycogen synthase kinase-3 inhibition is integral to Long Term Potentiation. Eur. J. Neurosci. 25(1):81-86. Valera, A.G., Díaz-Hernán<strong>de</strong>z, M., Hernán<strong>de</strong>z, F. and Lucas, J.J. (2007). Testing the possible inhibition of proteasome by direct interaction with ubiquitylated and aggregated huntingtin. Brain Res. Bull. 72: 121-123. García-Martínez, J.M., Pérez-Navarro, E., Xifró, X., Canals, J.M., Díaz-Hernán<strong>de</strong>z, M., Trioulier, Y., Brouillet, E., Lucas, J.J. and Alberch, J. (2007). BH3-only Proteins Bid and BimEL are Differentially Involved in Neuronal Dysfunction in Mouse Mo<strong>de</strong>ls of Huntington’s Disease. J. Neurosci. Res. 85: 2756-69. Goñi-Oliver, P., Lucas, J.J., Avila, J. and Hernán<strong>de</strong>z, F. (2007). N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation. J. Biol. Chem. 282: 22406-13. Ortega, Z., Diaz-Hernan<strong>de</strong>z, M. and Lucas, J.J. (2007). Is the ubiquitin-proteasome system impaired in Huntington’s disease? Cell. Mol. Life Sci. 64: 2245-57. Engel, T., Goñi-Oliver, P., Gómez <strong>de</strong> Barreda, E., Lucas, J.J., Hernán<strong>de</strong>z, F. and Avila, J. (2008). Lithium, a potential protective drug in Alzheimer’s disease. Neuro<strong>de</strong>gener Dis. 5: 247-9. Engel, T., Goñi-Oliver, P., Gómez-Ramos, P., Morán, M.A., Lucas, J.J., Avila, J. and Hernan<strong>de</strong>z, F. (2008). Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing FTDP-17 tau and GSK-3beta. Neuroscience 157: 772-80. Diaz-Hernan<strong>de</strong>z, M., Diaz-Hernan<strong>de</strong>z, J.I., Diez-Zaera, M., <strong>de</strong>l Puerto A., Lucas, J.J., Garrido, J.J. and Miras-Portugal, M.T. (2008). Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons. J. Cell Sci. 121: 3717-28. CBM 2007-2008