Nav1.5 on IonWorks HT - Molecular Devices

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A Representative Plate
<strong>Nav1.5</strong> on IonWorks HT: Current Size Distribution C6 Patch Plate Scan #1 1 60 0 Number of Cells 40 20 I mean = 1.51nA I med = 1.20nA SD = 1.11nA SEM = 0.06nA N = 335 Current (nA) -1 -2 -3 -4 -5 -6 5 10 15 20 25 30 Time (msec) 0 0 1 2 3 4 5 6 Current (nA)
Page 1 and 2: Compound Screening against Cardiac
Page 3 and 4: Voltage-gated Na + (Nav) Channels a
Page 5 and 6: RT4-B8 Has Endogenously Expressed <
Page 7 and 8: RT4-B8 Na Current Electrophysiology
Page 9 and 10: IonWorks HT: An Automated E-phys Pl
Page 11: Nav1.5 on IonWorks
Page 15 and 16: I-V Curve: IonWorks HT vs Patch-cla
Page 17 and 18: Nav1.5 on IonWorks
Page 19 and 20: Example Current Traces for Compound
Page 21 and 22: IC 50 Measurement: Correlation betw
Page 23 and 24: Nav1.5 on IonWorks
Page 25: Acknowledgements n Wyeth Research (

Nav1.5 on IonWorks HT - Molecular Devices

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