Nav1.5 on IonWorks HT - Molecular Devices

07.11.2014 • Views

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Nav1.5 on IonWorks HT - Molecular Devices

Nav1.5 on IonWorks HT - Molecular Devices

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Example Current Traces for Compound Well<br />

G8

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<str<strong>on</strong>g>Nav1.5</str<strong>on</strong>g> <strong>on</strong> I<strong>on</strong>Works <strong>HT</strong>: Plate View of Tetracaine Blocking <str<strong>on</strong>g>Nav1.5</str<strong>on</strong>g> >10% block >50% block >95% block Increasing Doses

Example Current Traces for Compound Well G8

Page 1 and 2: Compound Screening against Cardiac
Page 3 and 4: Voltage-gated Na + (Nav) Channels a
Page 5 and 6: RT4-B8 Has Endogenously Expressed <
Page 7 and 8: RT4-B8 Na Current Electrophysiology
Page 9 and 10: IonWorks HT: An Automated E-phys Pl
Page 11 and 12: Nav1.5 on IonWorks
Page 13 and 14: Nav1.5 on IonWorks
Page 15 and 16: I-V Curve: IonWorks HT vs Patch-cla
Page 17: Nav1.5 on IonWorks
Page 21 and 22: IC 50 Measurement: Correlation betw
Page 23 and 24: Nav1.5 on IonWorks
Page 25: Acknowledgements n Wyeth Research (