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National Collaborating Centre for Women's and Children's Health

National Collaborating Centre for Women's and Children's Health

National Collaborating Centre for Women's and Children's Health

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Contents<br />

1 Guideline summary 1<br />

1.1 Guideline development group membership, NCC-WCH staff <strong>and</strong> acknowledgements 1<br />

1.2 Foreword 2<br />

1.3 Care pathway 2<br />

1.4 Key priorities <strong>for</strong> implementation 11<br />

1.5 Recommendations 13<br />

1.6 Key research recommendations 29<br />

1.7 Research recommendations 32<br />

1.8 Schedule <strong>for</strong> updating the guideline 34<br />

2 Introduction 35<br />

2.1 Spasticity <strong>and</strong> co-existing motor disorders 35<br />

2.2 For whom is this guideline intended? 39<br />

2.3 Related NICE guidance 39<br />

3 Guideline development methodology 40<br />

3.1 Methodology 40<br />

3.2 Developing review questions <strong>and</strong> protocols <strong>and</strong> identifying evidence 40<br />

3.3 Reviewing <strong>and</strong> synthesising evidence 41<br />

3.4 Incorporating health economics 42<br />

3.5 Evidence to recommendations 43<br />

3.6 Stakeholder involvement 43<br />

3.7 Specific considerations <strong>for</strong> this guideline 43<br />

4 Physical therapy (physiotherapy <strong>and</strong>/or occupational therapy) 45<br />

5 Orthoses 79<br />

6 Oral drugs 111<br />

7 Botulinum toxin 130<br />

8 Intrathecal baclofen 171<br />

9 Orthopaedic surgery 208<br />

10 Selective dorsal rhizotomy 225<br />

11 <strong>Health</strong> economics 262<br />

11.1 Introduction 262<br />

11.2 Physical therapy (physiotherapy <strong>and</strong>/or occupational therapy) 263<br />

11.3 Orthoses 265<br />

11.4 Botulinum toxin 266<br />

11.5 Intrathecal baclofen 270<br />

11.6 Orthopaedic surgery 279<br />

11.7 Selective dorsal rhizotomy 280<br />

11.8 Overall conclusions 282<br />

12 References 284<br />

13 Abbreviations <strong>and</strong> glossary 291<br />

13.1 Abbreviations 291<br />

13.2 Glossary 293<br />

Appendices A to L are in separate files.<br />

iii

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