6228 Xylene Isomers - Total Refining & Chemicals

Material Safety Data Sheet
Section 1. Chemical Product and Company Identification
Product name
Supplier
Chemical Family Aromatic
CAS Registry
Number
Synonym
Xylenes - Mixed Isomers
Total Petrochemicals & Refining USA, Inc.
P O Box 674411
Houston,TX 77267-4411
1330-20-7
Mixed Xylenes, Xylol
In Case of
Emergency
Technical
Information
MSDS#
Validation
Date
Print Date
Chemtrec:
(800) 424-9300
Total Petrochemicals & Refining USA, Inc.:
(800) 322-3462
For non-emergency product information:
email product.stewardship@total.com
BC0012
2/5/2014
2/5/2014
Section 2. Hazards Identification
Emergency Overview
FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
MAY BE HARMFUL IF INHALED.
HARMFUL IF SWALLOWED. ASPIRATION HAZARD.
CONTAINS MATERIAL WHICH MAY CAUSE CANCER.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: CENTRAL NERVOUS SYSTEM,
RESPIRATORY TRACT, EYES, SKIN, LUNGS, KIDNEY, LIVER, GASTROINTESTINAL
TRACT
Routes of Entry
Absorbed through skin. Eye contact. Inhalation. Ingestion.
Potential Acute Health Effects
Eyes Irritation from vapors. Splash accidents have produced transient, superficial injury to the eye.
Skin
Inhalation
Ingestion
Potential Chronic Health
Effects
May cause skin irritation. Prolonged or repeated contact can defat the skin and lead to
irritation, cracking and/or dermatitis.
Short exposures to xylene in air may affect the central nervous system (CNS), causing
narcosis. Extremee exposure may cause death. Exposure to vapors may also cause irritation
of the respiratory system, eyes, and mucous membranes.
Aspiration hazard if swallowed. Can enter lungs and cause damage. Vomiting increases risk
of chemical pneumonia or pulmonary edema caused by aspiration. May be fatal if swallowed.
Central nervous system depression, a burning sensation in the oropharynx and stomach.
Vomiting.
Effects of chronic exposure to xylene are similar to those of acute exposure, particularly
central nervous system effects (based on animal studies). Chronic exposure to xylene may
cause liver and kidney effects.
CARCINOGENIC EFFECTS:
Classified A4 (Not classifiable for humans or animals.) by ACGIH, 3 (Not classifiable for
humans.) by IARC [xylene isomers].
Classified A3 (Proven for animals.) by ACGIH, 2B (Possible for humans.) by IARC
[ethylbenzene]. Classified None. by OSHA [ethylbenzene]
Medical Conditions
Aggravated by
Overexposure
Pre-existing disorders involving any target organs mentioned in this MSDS as being at risk
may be aggravated by over-exposure to this product.
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 2/8
Overexposure /Signs/
Symptoms
See Toxicological Information (Section 11)
_
Headache, tremors, apprehension, memory loss, weakness, dizziness, loss of appetite,
nausea, ringing in the ears, irritability, thirst, anemia, mucosal bleeding, enlarged liver, and
hyperplasia are reported when chronic inhalation of xylenes has occured. Repeated contact
with the skin can cause defatting dermatitis. Reversible eye damage, including vacuoles in
the cornea and conjuntiva, has occured with chronic xylene exposure.
Section 3. Composition and Information on Ingredients
Occupational exposure limits, if available, are listed in Section 8.
Substance Name
CAS #
% by Weight
xylene isomers 1330-20-7 >80
ethylbenzene 100-41-4 < 20
toluene 108-88-3

Xylenes - Mixed Isomers Page: 3/8
Section 6. Accidental Release Measures
_
Small Spill and Leak
Large Spill and Leak
Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Eliminate ignition sources and ventilate area.
Flammable liquid, insoluble in water. Contain spill and safely stop the flow. Warn personnel
to move away. Eliminate all sources of ignition. Ventilate. Absorb with DRY earth, sand or
other non-combustible material. Dike spill area and do not allow product to reach sewage
system or surface or ground water. Notify any reportable spill to authorities.Do not allow any
potentially contaminated water, including rain water, runoff from fire fighting or spills, to enter
any waterway, sewer or drain.
Section 7. Handling and Storage
Handling
Storage
Put on appropriate personal protective equipment (see Section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and processed.
Workers should wash hands and face before eating, drinking and smoking. Do not get in
eyes or on skin or clothing. Do not ingest. Avoid breathing vapor or mist. Use only with
adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Do not
enter storage areas and confined spaces unless adequately ventilated. Keep in the original
container or an approved alternative made from a compatible material, kept tightly closed
when not in use. Store and use away from heat, sparks, open flame or any other ignition
source. Use explosion-proof electrical (ventilating, lighting and material handling) equipment.
Use non-sparking tools. Take precautionary measures against electrostatic discharges. To
avoid fire or explosion, dissipate static electricity during transfer by grounding and bonding
containers and equipment before transferring material. Empty containers retain product
residue and can be hazardous. Do not reuse container.
Keep container tightly closed. Keep in a cool, well-ventilated place.
Take precautionary measures against electrostatic discharges.
Flammable materials should be stored in a separate safety storage cabinet or room.
All efforts should be made to prevent any leaks or spills. Storage tanks containing should be
engineered to prevent contact with water resources, as this material could contaminate the
water resources. Surface spills can reach groundwater through porous soil or cracked
surfaces. The storage tanks should be monitored regularly for leaks. Where spills or leaks are
possible, a comprehensive response plan should be developed and implemented.
Section 8. Exposure Controls/Personal Protection
Engineering Controls
Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure to airborne contaminants below any
recommended or statutory limits. The engineering controls also need to keep gas, vapor or
dust concentrations below any lower explosive limits. Use explosion-proof ventilation
equipment.
Personal Protection
Protective Clothing
(Pictograms)
Eyes Safety glasses with side shields.
Body Flame retardant clothing covering the entire body.
Respiratory Be sure to use a MSHA/NIOSH approved respirator or equivalent at high concentrations.
Hands Chemical resistant gloves if contact is possible.
Feet Shoes.
Personal Protection in
Case of a Large Spill
Product Name
Splash goggles. Full suit. Vapor and dust respirator. Boots. Gloves. A self contained
breathing apparatus should be used to avoid inhalation of the product. Suggested protective
clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 4/8
_
xylene isomers ACGIH TLV (United States, 2012).
TWA: 100 ppm 8 hour(s).
STEL: 150 ppm 15 minute(s).
OSHA PEL (United States, 11/2006).
TWA: 100 ppm 8 hour(s).
ethylbenzene ACGIH TLV (United States, 2012).
TWA: 20 ppm 8 hour(s).
OSHA PEL (United States, 11/2006).
TWA: 100 ppm 8 hour(s).
toluene OSHA PEL Z2 (United States, 11/2006).
TWA: 200 ppm 8 hour(s).
CEIL: 300 ppm
AMP: 500 ppm 10 minute(s).
ACGIH TLV (United States, 2012).
TWA: 20 ppm 8 hour(s).
Consult local authorities for acceptable exposure limits.
Section 9. Physical and Chemical Properties
Physical State and Appearance
Color
Odor
Odor Threshold
Molecular Weight
Molecular Formula
Boiling/Condensation Point
Melting/Freezing Point
Critical Temperature
Specific Gravity
Vapor Pressure
Vapor Density
Volatility
Evaporation Rate
VOC
Solubility in Water
Liquid.
Clear Colorless.
Sweet (aromatic) odor.
0.7 to 40 ppm
106
C8H1O
138.89°C (282°F)
-47.4°C (-53.3°F)
346°C (654.8°F)
0.87 (Water = 1)
8 mm of Hg (@ 25°C)
The highest known value is 3.66 (Air = 1) (Ethylbenzene). Weighted average: 3.
61 (Air = 1)
100% (v/v).
9.2 compared to Ether (anhydrous).
100 (%)
Negligible.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions of Instability
Incompatibility with
Various Substances
Hazardous
Decomposition Products
Hazardous
Polymerization
The product is stable.
No additional remark.
Extremely reactive or incompatible with acids.
Reactive with oxidizing agents.
Violent explosion may occur when chlorinating xylene with 1,3-dichloro-5,5-dimethyl-2,
4-imidazolidindione (dichlorohydrantoin). The haloimide undergoes immediate self
accelerating decomposition.
Carbon oxides (CO, CO2) and soot.
Will not occur.
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 5/8
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on
Humans
_
Product/ingredient name Result Species Dose Exposure
xylene isomers LD50 Dermal Rabbit >1700 mg/kg -
LD50 Intraperitoneal Rat 2459 mg/kg -
LD50 Oral Rat 4300 mg/kg -
LD50 Subcutaneous Rat 1700 mg/kg -
LC50 Inhalation Gas. Rat 5000 ppm 4 hours
ethylbenzene LD50 Dermal Rabbit >5000 mg/kg -
LD50 Dermal Rabbit 17800 uL/kg -
LD50 Oral Rat 3500 mg/kg -
LC50 Inhalation Vapor Rat 55000 mg/m3 2 hours
Effects of chronic exposure to xylene are similar to those of acute exposure, particularly
central nervous system effects (based on animal studies). Chronic exposure to xylene may
cause liver and kidney effects.
CARCINOGENIC EFFECTS:
Classified A4 (Not classifiable for humans or animals.) by ACGIH, 3 (Not classifiable for
humans.) by IARC [xylene isomers].
Classified A3 (Proven for animals.) by ACGIH, 2B (Possible for humans.) by IARC
[ethylbenzene]. Classified None. by OSHA [ethylbenzene].
Classified None. by OSHA [toluene]. Classified A4 (Not classifiable for humans or animals.)
by ACGIH, 3 (Not classifiable for humans.) by IARC [toluene].
Other Toxic Effects on
Humans
From the animal and human toxicology data, xylenes can be characterized as neurotoxic
chemicals at moderate to high doses inducing symptoms in humans of dizziness, headache,
nausea, and neuromuscular effects, speech impairment, and amnesia at high doses.
Aspiration into the lungs of even a small amount may cause severe injury, since its low
viscosity and surface tension will cause it to spread over a large surface of pulmonary tissue.
Special Remarks on
Toxicity to Animals
Results from acute oral, dermal or inhalation toxicity studies in rats and mice indicate that the
acute toxicity of xylene isomers and mixed xylenes is very low. Acute toxicity was typically
characterized by central nervous system depression. Animals exposed to xylene became
uncoordinated, prostrate and comatose at doses that produced mortality within the dose
group.
Section 12. Ecological Information
Ecotoxicity
Biodegradable/OECD
In repeated dose studies, the principle effects of xylenes were adaptive changes in the liver,
body weight changes, organ weight changes and altered motor coordination.
Ototoxicity (toxic effect on the structures of the ear, especially on its nerve supply) has been
reported in animals but not in humans.
Xylenes have not demonstrated genotoxic activity in animals or humans and do not appear to
be immunotoxic.
No adverse effects on reproductive performance were seen in laboratory studies and
developmental toxicity (fetal weight decrements) occurred at doses that were typically also
produced maternal toxic. Several developmental neurotoxicity studies have shown learning
deficits in offspring of treated animals which resolved as offspring matured. No conclusive
reproductive or developmental effects have been reported in human exposure studies.
Product/ingredient name Result Species Exposure
Xylene Isomers Acute EC50 1 mg/l Daphnia 48 hours
Acute IC50 2.2 mg/l Algae 72 hours
Acute LC50 2.6 mg/L Fish 96 hours
Biodegrades in soil and ground water (aerobic and anaerobic denitrifying conditions).
Mobility
The product evaporates into the atmosphere. This material floats on water. Because of its
high volatility, the product is unlikely to cause ground or water pollution.
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 6/8
Section 13. Disposal Considerations
Waste Information
Waste Stream
Consult your local or regional authorities.
_
Recover free liquid. Transfer to a safe disposal area in accordance with federal, state, and
local regulations. Recycle to process, if possible.
The classification of the product may meet the criteria for a hazardous waste.
Section 14. Transport Information
(for domestic bulk shipments, non-bulk shipments may differ)
DOT Classification for
Bulk Shipments (non bulk
shipments may differ)
Proper Shipping Name/
Description
UN Number
Packing Group
Marine Pollutant
DOT CLASS 3: Flammable liquid.
UN1993, Flammable Liquids n.o.s. (contains xylene isomers, ethylbenzene), 3, PG III RQ
UN1993
III
Not listed in Appendix B to 49CFR172.101
Hazardous Substances
Reportable Quantity
Special Provisions for
Transport
TDG Classification
IMO/IMDG Classification
ICAO/IATA Classification
USCG Proper Shipping
Name
Transport in bulk
according to Annex II of
MARPOL 73/78 and the
IBC Code
Xylene isomers 100 lbs. (45.4 kg); ethylbenzene 1000 lbs (454kg).
See codes as shown in 49 CFR 172.101 Column 7.
TDG CLASS 3: Flammable liquid.
TDG CLASS 9.2: Environmentally hazardous material.
IMDG CLASS 3.1: Flammable liquid (Low flash point).
IATA CLASS 3: Flammable liquid.
Xylenes, Ethylbenzene mixture
Product name: Xylenes/Ethylbenzene (10% or more) mixture (Xylene - Mixed Isomers)
Pollution category: Y
Ship type: 2G
Section 15. Regulatory Information
HCS Classification
U.S. Federal Regulations
Flammable liquid
Carcinogen
Target organ effects
TSCA 8(a) PAIR: p-xylene
TSCA 8(a) CDR Exempt/Partial exemption: Not determined
United States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: To the best of our knowledge,
there are no substances that would be at reportable levels for this regulation in this product.
SARA 302/304 emergency planning and notification: ethylbenzene
SARA 302/304/311/312 hazardous chemicals: Xylene Isomers
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Xylene
Isomers: Fire hazard, Immediate (acute) health hazard, Delayed (chronic) health hazard
SARA 313 Supplier Notification
This product contains the following EPCRA section 313 chemicals subject to the reporting
requirements of section 313 of the Emergency Planning and Community Right-to-Know Act
of 1986 (40 CFR 372 -Table 372.65).
Product name CAS number Concentration (%)
Xylene 1330-20-7 > 80
ethylbenzene 100-41-4 < 20
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 7/8
Clean Water Act (CWA) 307: ethylbenzene; toluene;
Clean Water Act (CWA) 311: Xylene
International Regulations
WHMIS (Canada) Class B-2: Flammable liquid
_
EINECS
DSCL (EEC)
CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: The following components are listed: Xylene
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
215-535-7
R10- Flammable.
R27- Very toxic in contact with skin.
R41- Risk of serious damage to eyes.
R37/38- Irritating to respiratory system and skin.
CEPA DSL/NDSL
International Lists
State Regulations
Section 16. Other Information
Label requirements
All components are listed or exempted.
Australia inventory (AICS): All components are listed or exempted.
China inventory (IECSC): All components are listed or exempted.
Japan inventory (ENCS): All components are listed or exempted.
Japan inventory (ISHL): Not determined.
Korea inventory (KECI): All components are listed or exempted.
New Zealand Inventory of Chemicals (NZIoC): All components are listed or exempted.
Philippines inventory (PICCS): All components are listed or exempted.
Florida substances: The following components are listed: Xylene
Massachusetts Substances: The following components are listed: Xylene
Michigan Critical Material: The following components are listed: Xylene
Minnesota Hazardous Substances: The following components are listed: Xylene
New Jersey Hazardous Substances: The following components are listed: Xylene
New York Acutely Hazardous Substances: The following components are listed: Xylene
(mixed); o-Xylene; p-Xylene; m-Xylene; Ethylbenzene
Pennsylvania RTK Hazardous Substances: The following components are listed: Xylene
WARNING: This product contains a chemical or chemicals known to the State of California to
cause cancer, birth defects or other reproductive harm.: ethylbenzene; toluene;
FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
MAY BE HARMFUL IF INHALED.
HARMFUL IF SWALLOWED. ASPIRATION HAZARD.
Hazardous Material
Information System
(U.S.A.)
CONTAINS MATERIAL WHICH MAY CAUSE CANCER.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: CENTRAL NERVOUS SYSTEM,
RESPIRATORY TRACT, EYES, SKIN, LUNGS, KIDNEY, LIVER, GASTROINTESTINAL
TRACT
Health
Fire Hazard
Reactivity
Personal Protection
*
2
3
0
National Fire
Protection
Association
(U.S.A.)
Health
2
3
0
Fire Hazard
Reactivity
Specific Hazard
Total Petrochemicals & Refining USA, Inc.

Xylenes - Mixed Isomers Page: 8/8
References
Chemtox Database
HSDB - Hazardous Substances Data Bank
_
Validated on 2/5/2014.
Printed 2/5/2014.
Chemtrec:
(800) 424-9300
Total Petrochemicals & Refining USA, Inc.:
(800) 322-3462
Notice to Reader
The information contained in this Material Safety Data Sheet (MSDS) / Safety Data Sheet (SDS) is believed by Total Petrochemicals & Refining USA, Inc.
(TPRI) to be accurate on the date issued. However, materials may present unknown hazards and should be used with caution. Final determination of
suitability and use of any material is the sole responsibility of the user. Neither TPRI nor any of its subsidiaries or affiliated companies assumes any liability
whatsoever for the accuracy or completeness of the information contained herein or reliance thereto. If the material is repackaged, the user is responsible and
must ensure that proper health, safety and other necessary information is included with the material and/or on the container. NO WARRANTIES OF ANY
KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE,
ARE MADE REGARDING THE MATERIALS OR THE INFORMATION CONTAINED IN THIS SDS. ALTERATION OF THIS DOCUMENT IS
STRICTLY PROHIBITED.
MSDS Name Xylene MSDS Code XYLENE
25.01
To obtain an electronic copy of this MSDS, please email: product.stewardship@total.com.
Total Petrochemicals & Refining USA, Inc.