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Peripheral B and T cell differentiation - University Institute of ...

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Leprosy:<br />

different clinical forms <strong>of</strong> the disease<br />

Lepromatous Leprosy:<br />

• Multiple, nodular lesions <strong>of</strong> the skin, in particular, <strong>of</strong> the<br />

face (”lion face").<br />

• Persistent bacteriemia, foamy <strong>cell</strong>-like lesions with<br />

numerous M. leprae present<br />

Tuberculoid Leprosy:<br />

• Singular, small macular lesions <strong>of</strong> the skin.<br />

• <strong>Peripheral</strong> nerves (e.g. N. ulnaris, peronealis, N.<br />

auricularis) are <strong>of</strong>ten affected sensory neuropathy.<br />

• Granuloma are frequent (with only low numbers <strong>of</strong><br />

M. leprae present)

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