FINAL PROGRAM - Imo

Scientific Posters
Scientific Posters
Scientific Poster 519
Evaluation of Choroidal Metastasis With OCT-Enhanced
Depth Imaging
Presenting Author: Hakan Demirci MD
Purpose: To evaluate the imaging features of choroidal metastasis with OCT enhanced
depth imaging (OCT-EDI). Methods: Retrospective analysis of 13 patients with choroidal
metastasis. Results: On OCT-EDI, irregular thickening of retina pigment epithelium was
observed in 8 patients (62%), and hyperreflective speckles in the subretinal fluid was observed
in 9 (69%). In all patients, choroidal metastatic tumor originated from the outer
layer (lamina vasculosa) of the choroid. In 3 cases that underwent treatment, the choroidal
metastasis became hyperreflective scar tissue. Conclusion: On OCT-EDI, choroidal metastasis
seems to develop in the outer layer of choroid that contains large, fenestrated
vessels. OCT-EDI might be used in the follow-up of thin choroidal metastatic tumor.
Scientific Poster 520
APAO Correlation Between the Repair of Cone Outer
Segment Tips and Visual Recovery After Epiretinal
Membrane Surgery
Presenting Author: Yuji Itoh MD
Co-Author(s): Makoto Inoue MD*, Tong-Sheng Lee MD, Akito Hirakata MD*
Purpose: To compare the recovery of photoreceptor cone outer segment tips (COST) line
and visual outcomes after epiretinal membrane (ERM) surgery. Methods: The diameter
of COST line defect was calculated by spectral domain OCT and compared with BCVA
after ERM surgery in 46 eyes. Prognostic factors to determine visual recovery were also
evaluated. Results: The smaller COST line defect was correlated with better BCVA in
all postoperative periods (P < .001). BCVA at 12 months after surgery was significantly
correlated with preoperative COST line defect (P < .01) and preoperative BCVA (P < .05).
Conclusion: Recovery of COST line may be related to visual recovery after ERM surgery.
Scientific Poster 521
En Face Imaging of Active and Quiescent Central Serous
Chorioretinopathy: A New Concept
Presenting Author: Mathieu Lehmann MD
Co-Author(s): Benjamin Wolff MD, Vivien Vasseur, Martine Mauget-Faysse MD*, Jose
A Sahel MD*
Purpose: To describe retinal and choroidal changes in acute and quiescent central serous
chorioretinopathy (CSC) observed with en face spectral domain OCT (SD-OCT). Methods:
Twenty-nine eyes with a diagnosis of CSC were prospectively scanned using en face SD-
OCT combined with EDI. Results: Seventy-nine percent had serous retinal detachment,
and 62% had pigment epithelial detachment. Subretinal hyperreflective deposits were
observed in 19 patients (65%). The mean choroidal thickness was 491 µm. 100% of the
patients demonstrated choroidal dilatation with en face OCT. Twenty percent had multiple
hyperreflective points located in the choriocapillary layer, and 2 patients had choroidal
cavitations. Conclusion: En face imaging using SD-OCT is an effective tool to understand
choroidal changes in active and quiescent CSC.
Scientific Poster 522
Correlation of Peripapillary Atrophy and Reticular Macular
Disease in Patients With Primary Geographic Atrophy
Resulting From AMD
Presenting Author: Marcela Marsiglia MD PHD
Co-Author(s): Sucharita Boddu, Srilaxmi Bearelly MD*, K Bailey Freund MD*, Lawrence
A Yannuzzi MD, R Theodore Smith MD**
Purpose: To correlate peripapillary atrophy (PPA) in AMD patients with geographic atrophy
(GA) with peripapillary reticular macular disease (RMD), aka reticular pseudodrusen.
Methods: Infrared imaging was used in 72 eyes of 57 patients with documented GA to
detect peripapillary RMD and/or PPA. Results: PPA was detected in 63 of 72 eyes (87.5%)
and peripapillary RMD was detected in 58 (80.5%). A significant correlation was found
between these entities (P = .011, Fisher exact test). Conclusion: The high concordance
between PPA and peripapillary RMD in AMD suggests a common disease mechanism,
consistent with impairment of posterior ciliary circulation around the optic nerve.
Scientific Poster 523
Comparing Indocyanine Green Angiography With Other
Imaging Modalities in Detecting Reticular Macular Disease
Presenting Author: Marcela Marsiglia MD PHD
Co-Author(s): Sucharita Boddu, Ana Rita B M Santos MS**, Rufino Silva MD MSC*,
Maria Da Luz Cachulo Damasceno MD, Jose G Cunha-Vaz MD PhD*, R Theodore Smith
MD**, Srilaxmi Bearelly MD*
Purpose: To compare indocyanine green angiography (ICG) with other scanning laser
ophthalmoscopy (SLO) imaging modalities in detecting reticular macular disease (RMD),
aka reticular pseudodrusen. Methods: Fellow eyes of 52 patients with unilateral CNV
were imaged with ICG, autofluorescence (AF), and infrared (IR) for presence and extent
of RMD. Results: ICG, AF, and IR detected RMD in 50.9%, 44.0%, and 35.5% of eyes,
and average areas of RMD detected were 27.9%, 17.4%, and 18.6%, respectively. ICG
and AF agreement was 90.0%, and between ICG and IR was 84.1%. Conclusion: ICG,
AF, and IR are highly concordant in detecting RMD, with high ICG sensitivity suggesting
choroidal involvement.
Scientific Poster 524
APAO Swept Source OCT Findings in Chronic Phase of Vogt-
Koyanagi-Harada Disease
Presenting Author: Ichiro Maruko MD
Co-Author(s): Yukinori Sugano MD**, Hiroshi Oyamada MD**, Tetsuju Sekiryu MD,
Tomohiro Iida MD*
Purpose: To evaluate choroidal and scleral thickness in chronic phase of Vogt-Koyanagi-
Harada disease (VKH) using swept source OCT. Methods: Choroidal and scleral thickness
was measured using OCT. Results: Fourteen eyes of 7 patients with chronic VKH were
examined. All eyes at the last examination had no subfoveal detachment and showed the
sunset glow fundus. Mean subfoveal choroidal and scleral thickness was 276 µm and 498
µm, respectively. Eight eyes with peripapillary atrophy (PPA) had thinner choroid compared
with 6 eyes without PPA (183 µm and 401 µm, P < .01). Conclusion: Although the choroid
in chronic VKH was thinner than in acute VKH, the sclera was restored. The choroidal thinning
might be associated with choroidal circulation because the cases with PPA especially
had thinner choroid.
Scientific Poster 525
APAO Retinal Blood Flow in Patients With Diabetic
Retinopathy Treated With Panretinal Photocoagulation
Presenting Author: Naoko Onizuka MD
Co-Author(s): Kiyoshi Suzuma MD, Yoshihisa Yamada, Masafumi Uematsu MD, Takashi
Kitaoka MD**
Purpose: To evaluate the retinal blood flow before and after panretinal photocoagulation
for diabetic retinopathy (DR). Methods: This study was conducted on 22 eyes of
15 patients. The retinal blood velocity at optic disc was evaluated as mean blur rate by
laser speckle flowgraphy, and photocoagulation was undergone by pattern scanning laser
(PASCAL). We compared the blood velocity before and after panretinal photocoagulation.
Results: The mean blood velocity significantly decreased to 71.2 ± 15% (P < .001) after
panretinal photocoagulation. The number of laser spots were significantly correlated with
decreases in mean blood velocity (R = 0.31, P = .021). Conclusion: The mean blood velocity
measured by laser speckle flowgraphy may be useful to examine an adequate number
of laser spots for DR.
Scientific Poster 526
Evaluation of Retinal Neurodegeneration With Spectral
Domain OCT in Multiple Sclerosis
Presenting Author: George J Parlitsis MD**
Co-Author(s): Aalya Fatoo MD, Susan A Gauthier DO*, Szilard Kiss MD*
Purpose: To evaluate retinal nerve fiber layer (RNFL) thickness, macular thickness (MT),
and macular volume (MV) in a large cohort of multiple sclerosis (MS) patients. Methods:
140 eyes of MS patients were prospectively evaluated using spectral domain OCT (SD-
OCT). Clinical data were correlated with RNFL and macular thickness. Results: MS eyes
showed peripapillary RNFL thinning compared with controls (91.7 µm vs. 152.8 µm, P <
.01), with more thinning in eyes with prior optic neuritis (P < .05). Nasal MT in MS eyes
was thinner than controls; however, global MT and MV were not significantly decreased
over an average follow-up period of 479 days. Conclusion: SD-OCT retinal neuronal layer
measurements may be an objective, quantifiable biomarker of neurodegeneration in MS
and optic neuritis.
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* The presenter has a financial interest. ** The presenter has not submitted financial interest disclosure information as of press date.
No asterisk indicates that the presenter has no financial interest.
Up-to-date information is available in the Program Search on the Academy’s website: www.aao.org/2012.