download pdf - Department of Pediatrics - University of Miami
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Sickle Cell Research: A Brief History<br />
Outside the Centers<br />
• 1983: PROPS, PROPS II<br />
<br />
<br />
<br />
NHLBI funded multi-center study <strong>of</strong> prophylactic<br />
penicillin<br />
Stopped early because <strong>of</strong> definitive outcomes<br />
Established prophylaxis as standard <strong>of</strong> care<br />
and led to SCD specific guidelines for later<br />
immunizations
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