Treatment of Nicotine Addiction in Primary Care
Treatment of Nicotine Addiction in Primary Care
Treatment of Nicotine Addiction in Primary Care
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NRT: <strong>Nicot<strong>in</strong>e</strong> nasal spray<br />
20<br />
Cigarette (1-2mg nicot<strong>in</strong>e)<br />
Venous lev els<br />
15<br />
10<br />
Plasma 5 nicot<strong>in</strong>e concentration (ng/ml)<br />
0<br />
M<strong>in</strong>utes<br />
0 30 60 90 120<br />
20<br />
15<br />
10<br />
5<br />
0<br />
<strong>Nicot<strong>in</strong>e</strong> nasal spray (1mg nicot<strong>in</strong>e)<br />
Plasma nicot<strong>in</strong>e concentration (ng/ml)<br />
0 30 60 90 M<strong>in</strong>utes120<br />
• Nasal sprays more closely mimic nicot<strong>in</strong>e<br />
from cigarettes<br />
• Common side effects with nasal sprays<br />
<strong>in</strong>clude nasal and throat irritation, cough<strong>in</strong>g<br />
and oral burn<strong>in</strong>g<br />
NRT <strong>in</strong>creases the odds <strong>of</strong> quitt<strong>in</strong>g about 1.5 to 2 fold<br />
Adapted from : Henn<strong>in</strong>gfield JE. <strong>Nicot<strong>in</strong>e</strong> medications for smok<strong>in</strong>g cessation. N Engl J Med 1995;333:1196-203
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