Reaction of Furan and Thiophene
Reaction of Furan and Thiophene
Reaction of Furan and Thiophene
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a) Oxidation<br />
Br 2 / CH 3 OH<br />
H<br />
O<br />
MeO<br />
H<br />
O OMe<br />
cis / trans<br />
2,5-Dihydro-2,5-dimethoxyfuran<br />
This reaction involves electrophilic addition <strong>of</strong> bromine in<br />
presence <strong>of</strong> methanol at 2 & 5 positions followed by<br />
substitution by methanol.<br />
<strong>Thiophene</strong> is oxidized by peracids to <strong>Thiophene</strong>-1-oxide <strong>and</strong><br />
2-hydroxythiophene oxide.<br />
S<br />
O<br />
S<br />
O<br />
OH