LOMOPRIM DS Tablet - Lomus Pharmaceuticals Pvt. Ltd.

LOMOPRIM DS Tablet/ Tablet/Suspension/ Drop
Dosage Forms/Composition
Cotrimoxazole
DS Tablet: Each tablet contains Trimethoprim 160 mg and Sulphamethoxazole 800 mg
Tablet: Each Lomorpim plain Tablet contains: Trimethoprim 80 mg and Sulphamethoxazole 400 mg
Suspension: Each 5 mlcontains Trimethoprim 40 mg and Sulphamethoxazole 200 mg
Drops: Each 2 ml contains Trimethoprim 40 mg and Sulphamethoxazole 200 mg
Pharmacological Index
Antibiotic, Sulfonamide Derivative
INDICATION
Oral treatment of urinary tract infections due to E. coli, Klebsiella and Enterobacter sp, M.
morganii, P. mirabilis and P. vulgaris; acute otitis media in children and acute exacerbations
of chronic bronchitis in adults due to susceptible strains of H. influenzae or S. pneumoniae;
prophylaxis of Pneumocystis carinii pneumonitis (PCP), traveler's diarrhea due to
enterotoxigenic E. coli or Cyclospora
Unlabeled use: Cholera and salmonella-type infections and nocardiosis; chronic prostatitis;
as prophylaxis in neutropenic patients with P. carinii infections, in leukemics, and in
patients following renal transplantation, to decrease incidence of gram-negative rod
infections
Pregnancy Risk Factor
C; D
Contraindications
Hypersensitivity to any sulfa drug or any component; porphyria; megaloblastic anemia due
to folate deficiency; infants 10%:
Dermatologic: Allergic skin reactions including rashes and urticaria, photosensitivity
Gastrointestinal: Nausea, vomiting, anorexia.
1% to 10%:

Dermatologic: Stevens-Johnson syndrome, toxic epidermal necrolysis (rare).
Hematologic: Blood dyscrasias.
Hepatic: Hepatitis .

per kg body mass daily which approximately corresponds to the following dosage according to age:
Children 6 - 12 years: Two medicine measures (10 mL) twice daily.
In the treatment of acute infections, co-trimoxazole should be administered for at least 5 days or for
at least 2 days after the symptoms have disappeared. If clinical improvement is not evident after
7 days therapy, the patient should be reassessed.
Patient Information
Take oral medication with 8 oz of water on an empty stomach (1 hour before or 2 hours
after meals) for best absorption. Finish all medication; do not skip doses. You may
experience increased sensitivity to sunlight; use sunblock, wear protective clothing and
dark glasses, or avoid direct exposure to sunlight. Small frequent meals, frequent mouth
care, sucking lozenges, or chewing gum may reduce nausea or vomiting. Report skin rash,
sore throat, blackened stool, or unusual bruising or bleeding immediately. Pregnancy
precautions: Inform prescriber if you are or intend to be pregnant.
LOMUS Drug Information Center
Lomus Pharmaceuticals Pvt. Ltd.
P.O. Box No 4506, Lomus House (Corporate office),
Kailash Chour, Lazimpat, Kathmandu, Nepal
Ph: 4436396 (Hunting Line). Fx: 977-1-4436395
E-mail: druginfo@lomus.com.np