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T. reesei - TNAU Genomics

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Summary<br />

Amongst the three CBHI mutant strains examined,<br />

CVt2 did not show major expression changes in the<br />

genes involved in the UPR and ERAD pathways<br />

CVt4 was showing a stress response at 48 h and<br />

CVt5 was already showing signs of stress at 12 h<br />

Only 2.5 to 6.3 % of the differentially expressed genes<br />

were common in each strain either at two time points or<br />

all three time points<br />

All mutant strains exhibited stress related physiological<br />

changes such as low biomass synthesis and thinner<br />

hyphae during cultivation when compared to the nonmutant<br />

CVt<br />

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19

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