T. reesei - TNAU Genomics

More documents

Recommendations

Info

Please purchase PPT to Flash on http://www.verydoc.com to remove this watermark. Conclusions The T. <strong>reesei</strong> proteasome seems to have a very similar structure to proteasomes isolated from other eukaryotic cells The use of mutant (misfolded) forms of a native highly secreted protein to study cellular protein quality control is a new approach The heterologous protein Venus did not cause any stress to the strain in the culture conditions used when compared to the non-transformant Rut-C30 Please purchase PPT to Flash on http://www.verydoc.com to remove this watermark. 24
Please purchase PPT to Flash on http://www.verydoc.com to remove this watermark. Conclusions cont… Of all the differentially expressed genes identified, 23-50% had no match to known genes or proteins, or hypothetical genes or proteins Expression of a mutant CBHI decreased transcription and CBHI activity The known ER-stress-induced chaperones, BiP, PDI and PPI were found to be affected in strain CVt4 (48 h) CVt5 responded by mainly up-regulating the genes involved in the ERAD pathway Please purchase PPT to Flash on http://www.verydoc.com to remove this watermark. 25
Page 1 and 2: Please purchase PPT to Flash on htt
Page 23: Please purchase PPT to Flash on htt
Page 45: Please purchase PPT to Flash on htt

T. reesei - TNAU Genomics

Create successful ePaper yourself

Delete template?

Save as template?