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WHO Drug Information Vol. 20, No. 4, 2006 - World Health ...

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<strong>WHO</strong> <strong>Drug</strong> <strong>Information</strong>, <strong>Vol</strong>. <strong>20</strong>, <strong>No</strong>. 4, <strong>20</strong>06 Proposed INN: List 96<br />

alvespimycinum<br />

alvespimycin (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(dimethylamino)=<br />

ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-<br />

3,<strong>20</strong>,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-<br />

9-yl carbamate<br />

antineoplastic<br />

alvespimycine carbamate de (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-<br />

(diméthylamino)éthyl]amino}-13-hydroxy-8,14-diméthoxy-<br />

4,10,12,16-tetraméthyl-3,<strong>20</strong>,22-trioxo-2-azabicyclo[16.3.1]docosa-<br />

1(21),4,6,10,18-pentaén-9-yle<br />

antinéoplasique<br />

alvespimicina carbamato de (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-[[2-<br />

(dimetilamino)etil]amino]-13-hidroxi-4,10,12,16-tetrametil-<br />

8,14-dimetoxi-3,<strong>20</strong>,22-trioxo-2-azabiciclo[16.3.1]docosa-<br />

1(21),4,6,10,18-pentaen-9-ilo<br />

antineoplásico<br />

C32H48N4O8<br />

amifampridinum<br />

amifampridine pyridine-3,4-diamine<br />

potassium channel blocker<br />

N<br />

O<br />

N<br />

H<br />

CH 3<br />

O<br />

H<br />

NH<br />

H3CO H3C O HO H<br />

H H H<br />

CH3 OCH3 CH3 amifampridine pyridine-3,4-diamine<br />

bloqueur des canaux potassiques<br />

amifampridina piridina-3,4-diamina<br />

bloqueador de los canales de potasio<br />

H 3C<br />

C5H7N3<br />

N<br />

CH 3<br />

NH 2<br />

NH 2<br />

467214-<strong>20</strong>-6<br />

O NH 2<br />

H<br />

O<br />

54-96-6<br />

283

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