WHO Drug Information Vol. 20, No. 4, 2006 - World Health ...

Proposed INN: List 96 WHO Drug Information, Vol. 20, No. 4, 2006
isavuconazonii chloridum
isavuconazonium chloride 1-{(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-
2-(2,5-difluorophenyl)-2-hydroxybutyl}-4-{(1RS)-1-[methyl-
(3-{[(methylamino)acetyloxy]methyl}pyridin-2-yl)carbamoyloxy]ethyl}-
1,2,4-triazolium chloride
antifungal
288
chlorure d'isavuconazonium chlorure de 1-{(2R,3R)-3-[4-(4-cyanophényl)-1,3-thiazol-2-yl]-
2-(2,5-difluorophényl)-2-hydroxybutyl}-4-{(1RS)-1-[méthyl-
(3-{[(méthylamino)acétyloxy]méthyl}pyridin-2-yl)carbamoyloxy]éthyl}-
1,2,4-triazolium
antifongique
cloruro de isavuconazonio cloruro de 1-{(2R,3R)-3-[4-(4-cianofenil)-1,3-tiazol-2-il]-
2-(2,5-difluorofenil)-2-hidroxibutil}-4-{(1RS)-1-[metil-
(3-{[(metilamino)acetiloxi]metil}piridin-2-il)carbamoiloxi]etil}-
1,2,4-triazolium
antifúngico
C35H35ClF2N8O5S
H 3C
NC
H
N
O
O
N
N
S
N
CH3 F
HO
H CH3N O
H
N +
N
O * CH3 F
Cl -
338990-84-4
and epimer at C*
et l'épimère en C*
y el epímero al C*
linaclotidum
linaclotide [9-L-tyrosine]heat-stable enterotoxin (Escherichia coli)-(6-19)-peptide
guanylate cyclase-C agonist
linaclotide [9-L-tyrosine]entérotoxine thermostable (Escherichia coli)-
(6-19)-peptide
agoniste de la guanylate cyclase-C
linaclotida [9-L-tirosina]enterotoxina termoestable (Escherichia coli)-
(6-19)-péptido
agonista de la guanilato ciclasa-C
C59H79N15O21S6
H Cys Cys Glu Tyr Cys Cys Asn Pro
Ala Cys Thr Gly Cys Tyr OH
10
851199-59-2