Examples of ethnicity and geography issues in global clinical trials ...
Examples of ethnicity and geography issues in global clinical trials ...
Examples of ethnicity and geography issues in global clinical trials ...
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Primary endpo<strong>in</strong>t <strong>in</strong> predef<strong>in</strong>ed subgroups (3)<br />
Characteristic<br />
Hazard Ratio<br />
(95% CI)<br />
Total<br />
Patients<br />
KM % at<br />
Month 12<br />
Ti.<br />
Cl.<br />
HR (95% CI)<br />
Antiplatelet Therapy Prior to Index Event<br />
Clopidogrel ± ASA<br />
1397 15.8 17.8 0.95 (0.73, 1.24)<br />
ASA<br />
5024 11.8 14.0 0.84 (0.71, 0.98)<br />
None<br />
12,147 8.2 10.0 0.82 (0.73, 0.93)<br />
ASA on Day <strong>of</strong> R<strong>and</strong>.<br />
No<br />
927 11.6 13.8 0.87 (0.60, 1.27)<br />
Yes<br />
17,697 9.7 11.6 0.84 (0.77, 0.93)<br />
GPIIb/IIIa (IE to End <strong>of</strong> Index Hosp.)<br />
No<br />
13,562 9.7 11.9 0.82 (0.74, 0.92)<br />
Yes<br />
5062 10.0 11.1 0.90 (0.76, 1.07)<br />
Race<br />
Caucasian<br />
Black<br />
17,077<br />
229<br />
9.5<br />
13.0<br />
11.2<br />
19.6<br />
0.85 (0.77, 0.94)<br />
0.63 (0.32, 1.23)<br />
Oriental<br />
1096 12.5 14.8 0.87 (0.62, 1.21)<br />
Other<br />
221 14.4 21.4 0.63 (0.33, 1.21)<br />
Weight by Gender-specific Median<br />
Males
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