Examples of ethnicity and geography issues in global clinical trials ...

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Effect Modifier Analysis Entire cohort analysis Day-4 landmark analysis
Primary Efficacy Outcome US and Non-US and by ASA Dose *Hazard ratio not calculated due to small number of events.
Page 1 and 2: Examples of ethnicity and geography
Page 3 and 4: Trial Design Placebo NSTE Acute Cor
Page 5 and 6: Subgroups GUSTO Moderate/Severe Pri
Page 7 and 8: PLATO study design NSTE-ACS (modera
Page 9 and 10: Cumulative incidence (%) PLATO: pri
Page 11 and 12: Primary endpoint in predefined subg
Page 13 and 14: Primary endpoint in predefined subg
Page 15 and 16: No Systematic Errors • US and ROW
Page 17: High-dose Aspirin Use: Landmark Tim
Page 21 and 22: Summary • In PLATO, ticagrelor re
Page 23 and 24: RE-LY ® - participating countries
Page 25 and 26: Primary Outcome Sub-groups (3) Dabi
Page 27 and 28: % per year Stroke / SSE According t
Page 30 and 31: Ethnicity and geography issues in g

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